How much is the bus ticket from San Diego to Chicago?

The cheapest coach tickets from San Diego to Chicago start from £108. The average price for this route is around £219. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from San Diego to Chicago?

The average bus journey time from San Diego to Chicago is 2d 6h, covering a distance of 1727 miles. The fastest bus can take you there in 2d 4h and is operated by FlixBus .

Which bus companies service the San Diego to Chicago route?

Several major bus companies operate on this route with 27 buses available per day, including services from Greyhound , Amtrak , FlixBus .

What is the earliest and latest departure time for the bus from San Diego to Chicago?

The earliest bus departs from San Diego to Chicago at 06:45. And the latest bus departs at 19:35.

What are the CO₂ emissions for the bus trip from San Diego to Chicago?

A bus journey from San Diego to Chicago produces an estimated 70 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Which is the best bus company from San Diego to Chicago?

According to Busbud customers, the highest-rated bus company on this route is Amtrak , with an average rating of 4.1 out of 5 stars based on 5654 reviews.

Which company has the best Wi-Fi from San Diego to Chicago?

Based on Busbud reviews, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

Which bus company offers the most punctual service from San Diego to Chicago?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from San Diego to Chicago?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak , with a cleanliness rating of 4.5 out of 5 stars.

Bus San Diego to Chicago from £106 | Refundable Tickets

Next bus departures

Next departures from San Diego to Chicago on 26 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	14:10	UCSD Health La Jolla Station	2d 2h	18:35	Chicago 95Th & Dan Ryan	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	14:10	UCSD Health La Jolla Station	2d	16:30	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15	San Diego (Old Town-FlixBus)	2d 2h	16:30	Downtown Greyhound Station	No tags
	Bus	19:35	Greyhound Bus Stop	2d 6h	04:10	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	15:55	San Diego (Old Town-FlixBus)	2d 10h	04:10	Downtown Greyhound Station	No tags

Next departures from San Diego to Chicago on 27 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	14:10	UCSD Health La Jolla Station	2d	16:30	Downtown Greyhound Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15	San Diego (Old Town-FlixBus)	2d 2h	16:30	Downtown Greyhound Station	No tags
	Bus	19:35	Greyhound Bus Stop	2d 6h	04:10	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	15:55	San Diego (Old Town-FlixBus)	2d 10h	04:10	Downtown Greyhound Station	No tags
	Bus	19:35	Greyhound Bus Stop	2d 10h	08:00	537-517 W. Jackson Blvd	No tags

Next departures from San Diego to Chicago on 28 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	19:35	Greyhound Bus Stop	2d 6h	04:10	Downtown Greyhound Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	14:10	UCSD Health La Jolla Station	2d	16:30	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15	San Diego (Old Town-FlixBus)	2d 2h	16:30	Downtown Greyhound Station	No tags
	Bus	19:35	Greyhound Bus Stop	2d 10h	08:00	537-517 W. Jackson Blvd	No tags
FlixBus + Greyhound Lines, Inc.	Bus	15:55	San Diego (Old Town-FlixBus)	2d 10h	04:10	Downtown Greyhound Station	No tags

Next departures from San Diego to Chicago on 29 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	16:15	UCSD Health La Jolla Station	2d 9h	04:10	Downtown Greyhound Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	14:10	UCSD Health La Jolla Station	2d	16:30	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15	San Diego (Old Town-FlixBus)	2d 2h	16:30	Downtown Greyhound Station	No tags
	Bus	19:35	Greyhound Bus Stop	2d 6h	04:10	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	15:55	San Diego (Old Town-FlixBus)	2d 10h	04:10	Downtown Greyhound Station	No tags

Next departures from San Diego to Chicago on 30 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	14:10	UCSD Health La Jolla Station	2d	16:30	Downtown Greyhound Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15	San Diego (Old Town-FlixBus)	2d 2h	16:30	Downtown Greyhound Station	No tags
	Bus	19:35	Greyhound Bus Stop	2d 6h	04:10	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	12:15	San Diego (Old Town-FlixBus)	2d 17h	08:00	537-517 W. Jackson Blvd	No tags
	Bus	19:35	Greyhound Bus Stop	2d 10h	08:00	537-517 W. Jackson Blvd	No tags

Next departures from San Diego to Chicago on 31 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	19:35	Greyhound Bus Stop	2d 6h	04:10	Downtown Greyhound Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	14:10	UCSD Health La Jolla Station	2d	16:30	Downtown Greyhound Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	12:15	San Diego (Old Town-FlixBus)	2d 2h	16:30	Downtown Greyhound Station	No tags
	Bus	19:35	Greyhound Bus Stop	2d 10h	08:00	537-517 W. Jackson Blvd	No tags
FlixBus + Greyhound Lines, Inc.	Bus	12:15	San Diego (Old Town-FlixBus)	2d 17h	08:00	537-517 W. Jackson Blvd	No tags

Last refresh of the prices: Yesterday at 10:46 PST.

Compare 2 ways to travel from San Diego to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 2 days, 6 hours 20 minutes and with fares starting at just £108, it presents an excellent value for a comfortable ride.

27bus per day

2d 6hAverage duration

1727 milesDistance

70kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£108 - £490	Average duration2d 6h	CO₂ emissions 70kg CO₂e
Train	Average price£141 - £1,176	Average duration1d 22h	CO₂ emissions 254kg CO₂e

Where are the popular stops in San Diego and Chicago?

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
Visit page
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

Greyhound

3.5/587,452 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

Amtrak

4/55,677 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

WiFi3.6

FlixBus

3.5/511,741 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling by bus from San Diego, CA, US to Chicago

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from San Diego to Chicago?
The cheapest coach tickets from San Diego to Chicago start from £108. The average price for this route is around £219. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from San Diego to Chicago?
The average bus journey time from San Diego to Chicago is 2d 6h, covering a distance of 1727 miles. The fastest bus can take you there in 2d 4h and is operated by FlixBus.
Which bus companies service the San Diego to Chicago route?
Several major bus companies operate on this route with 27 buses available per day, including services from Greyhound, Amtrak, FlixBus.
What is the earliest and latest departure time for the bus from San Diego to Chicago?
The earliest bus departs from San Diego to Chicago at 06:45. And the latest bus departs at 19:35.
What are the CO₂ emissions for the bus trip from San Diego to Chicago?
A bus journey from San Diego to Chicago produces an estimated 70 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from San Diego to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5654 reviews.
Which company has the best Wi-Fi from San Diego to Chicago?
Based on Busbud reviews, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company offers the most punctual service from San Diego to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Diego to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

24/12

£167

25/12

£386

Today

£426

27/12

£208

28/12

£240

29/12

£257

30/12

£203

31/12

£180

The cheapest trip from San Diego, CA, US to Chicago was searched and found on 24 Dec 2025 with a price of £167

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Chicago as early as possible.

You can expect to pay from £167 to £546 for a bus ticket from San Diego, CA, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £180, which is on 2025-12-31.