Next departures from Prague to Frankfurt am Main on 27 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Prague (Central Bus Station Florenc)
Frankfurt Hbf
Cheapest
Florenc
Frankfurt - Main bus station
Fastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Flixbus + Flixtrain
PRG Airport
Südbahnhof
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Next departures from Prague to Frankfurt am Main on 28 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Florenc
Frankfurt - Main bus station
CheapestFastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Flixbus + Flixtrain
PRG Airport
Südbahnhof
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Next departures from Prague to Frankfurt am Main on 29 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Florenc
Frankfurt central
Cheapest
Florenc
Frankfurt - Main bus station
Fastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Flixbus + Flixtrain
PRG Airport
Südbahnhof
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Next departures from Prague to Frankfurt am Main on 30 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Florenc
Frankfurt - Main bus station
CheapestFastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Flixbus + Flixtrain
PRG Airport
Südbahnhof
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Flixbus + Flixtrain
Prague (Central Bus Station Florenc)
Südbahnhof
No tags
Next departures from Prague to Frankfurt am Main on 1 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Florenc
Frankfurt - Main bus station
CheapestFastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Next departures from Prague to Frankfurt am Main on 2 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Florenc
Frankfurt - Main bus station
CheapestFastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Next departures from Prague to Frankfurt am Main on 3 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Florenc
Frankfurt - Main bus station
CheapestFastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Next departures from Prague to Frankfurt am Main on 4 December
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Florenc
Frankfurt - Main bus station
CheapestFastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Flixbus + Flixtrain
PRG Airport
Südbahnhof
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Last refresh of the prices: Today at 06:27 CET.
Compare 3 ways to travel from Prague to Frankfurt am Main
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as a good way to reach Frankfurt am Main. The journey takes about 5 hours 10 minutes and with fares starting at just £19, it presents an excellent value for a comfortable ride.
Based on 11454 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £23
Based on 1057 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the departure location and the value for money but often complained with the Wi-Fi. RegioJet ticket prices on this trip start at £26
Based on 18 reviews, the company was rated 3.6 stars on Busbud. Travellers were especially satisfied with the seats and the temperature but often complained with the Wi-Fi. Racic Eurobus ticket prices on this trip start at £27
Based on 19 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the staff and the seats but often complained with the timeliness. KLR Bus ticket prices on this trip start at £18
Based on 11165 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. BlaBlaCar Bus ticket prices on this trip start at £23
LEX CLUB offers 1 daily departures, and you can find tickets starting at £25. The quickest ride takes around 710. LEX CLUB offers a cost-effective solution to get you where you need to be.
Frequently asked questions about travelling by bus from Prague to Frankfurt am Main
What's the distance between Prague and Frankfurt am Main by coach?
The journey from Prague to Frankfurt am Main by coach covers an approximate distance of 254 miles (410 km).
How can I travel from Prague to Frankfurt am Main avoiding air travel?
You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
25/11
£26
26/11
£27
Today
£26
28/11
£28
29/11
£22
30/11
£33
01/12
£24
02/12
£24
The cheapest trip from Prague to Frankfurt am Main was searched and found on 29 Nov 2025 with a price of £22
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Frankfurt am Main as early as possible.
You can expect to pay from £22 to £80 for a bus ticket from Prague to Frankfurt am Main based on the last 2 days. You can expect to find the cheapest price for the trip at £22, which is on 2025-11-29.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.