Next departures for Prague to Frankfurt am Main on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Prague (Central Bus Station Florenc)
Frankfurt Hbf
Cheapest
Florenc
Frankfurt - Main bus station
Fastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Main Railway Station)
FRA Frankfurt airport
No tags
Next departures for Prague to Frankfurt am Main on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Florenc
Frankfurt - Main bus station
CheapestFastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Next departures for Prague to Frankfurt am Main on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Prague (Central Bus Station Florenc)
Frankfurt Hbf
Cheapest
Florenc
Frankfurt - Main bus station
Fastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Flixbus + Flixtrain
PRG Airport
Südbahnhof
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Next departures for Prague to Frankfurt am Main on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Prague (Central Bus Station Florenc)
Frankfurt Hbf
Cheapest
Florenc
Frankfurt - Main bus station
Fastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Flixbus + Flixtrain
PRG Airport
Südbahnhof
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Next departures for Prague to Frankfurt am Main on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Prague (Central Bus Station Florenc)
Frankfurt Hbf
Cheapest
Florenc
Frankfurt - Main bus station
Fastest
Florenc
Frankfurt central
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Flixbus + Flixtrain
PRG Airport
Südbahnhof
No tags
Next departures for Prague to Frankfurt am Main on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Florenc
Frankfurt - Main bus station
CheapestFastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Flixbus + Flixtrain
PRG Airport
Südbahnhof
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Flixbus + Flixtrain
Prague (Central Bus Station Florenc)
Südbahnhof
No tags
Next departures for Prague to Frankfurt am Main on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Florenc
Frankfurt - Main bus station
CheapestFastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Next departures for Prague to Frankfurt am Main on December 2
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Florenc
Frankfurt - Main bus station
CheapestFastest
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Prague (Central Bus Station Florenc)
FRA Frankfurt airport
No tags
Last refresh of the prices: Today at 6:11 AM CET.
Compare 3 ways to go from Prague to Frankfurt am Main
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as a good way to reach Frankfurt am Main. The journey takes about 5 hours 10 minutes, and with fares starting at just $35, it presents an excellent value for a comfortable ride.
Based on 11440 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at $43
Based on 1057 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the departure location and the value for money but often complained with the WiFi. RegioJet ticket prices on this trip start at $48
Based on 18 reviews, the company was rated 3.6 stars on Busbud. Travellers were especially satisfied with the seats and the temperature but often complained with the WiFi. Racic Eurobus ticket prices on this trip start at $50
Based on 19 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the staff and the seats but often complained with the timeliness. KLR Bus ticket prices on this trip start at $33
Based on 11159 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. BlaBlaCar Bus ticket prices on this trip start at $43
LEX CLUB offers 1 daily departures, and you can find tickets starting at $46. The quickest ride takes around 710. LEX CLUB offers a cost-effective solution to get you where you need to be.
Frequently asked questions about travelling from Prague to Frankfurt am Main by bus
How far is Prague from Frankfurt am Main?
It's about 410 km (254 miles) from Prague to Frankfurt am Main.
What are the departure and arrival locations for buses traveling from Prague to Frankfurt am Main?
Buses departing from PRG Airport in Prague will take you to Frankfurt Airport in Frankfurt am Main.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-23
$69
11-24
$52
Today
$48
11-26
$44
11-27
$44
11-28
$47
11-29
$41
11-30
$67
The cheapest trip from Prague to Frankfurt am Main was searched and found on Nov 29, 2025 with a price of $41
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Frankfurt am Main, as early as possible.
You can expect to pay from $41 to $180 for a bus ticket from Prague to Frankfurt am Main based on the last 2 days. You can expect to find the cheapest price for the trip at $41 which is on 2025-11-29.
The cheapest trip from Prague to Frankfurt am Main was searched and found on Nov 29, 2025 with a price of $41
