Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Orlando Health / Amtrak Station | Greenville Station | CheapestFastest | ||||
| Train | Orlando Health / Amtrak Station | Greenville Station | No tags | ||||
| Train | Orlando Health / Amtrak Station | Greenville Station | No tags | ||||
| Train | Orlando Health / Amtrak Station | Greenville Station | No tags | ||||
| Train | Orlando Health / Amtrak Station | Greenville Station | No tags |
Last refresh of the prices: Today at 11:12 AM EST.
Compare 2 ways to go from Orlando to Greenville
Among the sustainable travel choices, the Bus stands out as a good way to reach Greenville. The journey takes about 12 hours 55 minutes, and with fares starting at just $98, it presents an excellent value for a comfortable ride.
Train companies
Based on 5750 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi‑Fi. Amtrak ticket prices on this trip start at $181
Frequently asked questions about travelling from Orlando to Greenville, SC by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Orlando to Greenville?
The cheapest train tickets from Orlando to Greenville start at $181. The average price for this train route is around $399. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Orlando to Greenville?
The average train trip from Orlando to Greenville takes 1d 10h and covers 711 km. The quickest train gets you there in 1d 10h and is operated by Amtrak.
Which train operators serve the Orlando to Greenville route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Orlando to Greenville?
The earliest train from Orlando to Greenville departs at 12:36pm. The latest train departs at 6:50pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Greenville, SC was searched and found on Jan 25, 2026 with a price of $225To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Orlando to Greenville, SC, as early as possible.
You can expect to pay from $225 to $1,672 for a train ticket from Orlando to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $241 which is on 2026-01-28.
