Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Greyhound Amtrak Station | Depew Station | No tags | ||||
| Train | Greyhound Amtrak Station | Depew Station | No tags | ||||
| Train | Greyhound Amtrak Station | Depew Station | No tags | ||||
| Train | Greyhound Amtrak Station | Depew Station | No tags | ||||
| Train | Greyhound Amtrak Station | Depew Station | No tags |
Compare 2 ways to go from Indianapolis to Buffalo
Among the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 16 hours 45 minutes, and with fares starting at just $135, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Indianapolis and Buffalo, NY?
Train companies
Based on 5657 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $246
Frequently asked questions about travelling from Indianapolis to Buffalo, NY by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Indianapolis to Buffalo?
The cheapest train tickets from Indianapolis to Buffalo start at $246. The average price for this train route is around $315. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Indianapolis to Buffalo?
The average train trip from Indianapolis to Buffalo takes 1d 2h and covers 713 km. The quickest train gets you there in 1d 2h and is operated by Amtrak.
Which train operators serve the Indianapolis to Buffalo route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Indianapolis to Buffalo?
The earliest train from Indianapolis to Buffalo departs at 6:00am. The latest train departs at 6:00am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Buffalo, NY was searched and found on Dec 20, 2025 with a price of $303To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Indianapolis to Buffalo, NY, as early as possible.
You can expect to pay from $303 to $1,080 for a train ticket from Indianapolis to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $303 which is on 2025-12-20.
