Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Winston Salem Greyhound Bus Station | Downtown Gray & Smith | Cheapest | |||||
 | Winston-salem, (NC - Tienda Mexican El Crystal) | Houston Lockwood, (TX - TBC Lockwood) | Fastest | |||||
 | Winston Salem Greyhound Bus Station | Amtrak Station | No tags | |||||
 | Winston Salem Greyhound Bus Station | Houston Bus Station | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Winston Salem Greyhound Bus Station | Downtown Gray & Smith | No tags |
Last refresh of the prices: Last Friday at 10:26 PM EST.
Get from Winston-Salem to Houston
The journey takes about 1 day, 4 hours 10 minutes, and with fares starting at just $137, it presents an excellent value for a comfortable ride.
Where are the popular stops in Winston-Salem and Houston?
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B
Downtown Greyhound Station
2121 Main St, Houston, TX 77002 - C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
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Frequently asked questions about travelling from Winston-Salem to Houston, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Winston-Salem to Houston?
The cheapest bus tickets from Winston-Salem to Houston start from $137. The average price for this route is around $268. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Winston-Salem to Houston?
The average bus travel time from Winston-Salem to Houston is 1d 4h, covering a distance of 1569 km. The quickest bus can get you there in 18h 31m and is operated by Tornado Bus.
Which bus companies service the Winston-Salem to Houston route?
Several major bus companies operate on this route with 15 buses available per day, including services from Greyhound, Tornado Bus, Amtrak.
What are the earliest and latest departure times for the bus from Winston-Salem to Houston?
The earliest bus departs from Winston-Salem to Houston at 6:55am. And the latest bus departs at 6:15pm.
What are the CO₂ emissions for the bus trip from Winston-Salem to Houston?
A bus trip from Winston-Salem to Houston generates an estimated 39 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Winston-Salem to Houston?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5696 reviews.
Which bus company has the best Wi-Fi from Winston-Salem to Houston?
Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 4.1.
Which bus company has the best on-time performance from Winston-Salem to Houston?
According to Busbud traveller reviews, the most punctual bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Winston-Salem to Houston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Winston-Salem to Houston, US was searched and found on Jan 19, 2026 with a price of $207To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Houston, US, as early as possible.
You can expect to pay from $207 to $1,403 for a bus ticket from Winston-Salem to Houston, US based on the last 2 days. You can expect to find the cheapest price for the trip at $207 which is on 2026-01-19.
Usually Tornado Bus, Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
