Next departures for Syracuse to Detroit on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound + FlixBus
Bus
Syracuse (Regional Transportation Center)
Detroit Bus Station
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Greyhound + FlixBus
Bus
Syracuse (Regional Transportation Center)
Detroit Bus Station
No tags
Bus
SYR Airport
Indian Trails Bus Terminal
No tags
Bus
SYR Airport
Indian Trails Bus Terminal
No tags
Bus
Syracuse University
Indian Trails Bus Terminal
No tags
Compare 2 ways to go from Syracuse to Detroit
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Detroit. The journey takes about 11 hours 15 minutes, and with fares starting at just $113, it presents an excellent value for a comfortable ride.
Based on 87382 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $113
Based on 4412 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. New York Trailways ticket prices on this trip start at $273
Based on 1126 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the ticket access and the cleanliness but often complained with the WiFi. Adirondack Trailways ticket prices on this trip start at $423
Based on 11376 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $209
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210Syracuse University
Frequently asked questions about travelling from Syracuse, US to Detroit, MI by bus
What is the travel distance from Syracuse to Detroit?
The distance between Syracuse and Detroit is approximately 570 km (354 miles).
What are the departure and arrival locations for buses traveling from Syracuse to Detroit?
Buses departing from Regional Transportation Center in Syracuse will take you to Detroit Bus Station in Detroit.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-17
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11-18
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Today
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11-20
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11-21
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11-22
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11-23
$88
11-24
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The cheapest trip from Syracuse, US to Detroit, MI was searched and found on Nov 23, 2025 with a price of $88
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Detroit, MI, as early as possible.
You can expect to pay from $88 to $88 for a bus ticket from Syracuse, US to Detroit, MI based on the last 2 days. You can expect to find the cheapest price for the trip at $88 which is on 2025-11-23.
What's the cheapest way to go from Syracuse, US to Detroit, MI?
The bus is the cheapest travel choice for this destination