Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Gateway Station | Charlotte Bus Station | Cheapest | ||||
 | Bus | Gateway Station | Charlotte (Freedom Dr) | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gateway Station | Charlotte Bus Station | No tags | ||||
 | Bus | Gateway Station | Charlotte Bus Station | No tags | ||||
| Bus | Gateway Station | Charlotte Bus Station | No tags |
Last refresh of the prices: Yesterday at 1:33 PM CST.
Compare 2 ways to go from St. Louis to Charlotte
Among the sustainable travel choices, the bus stands out as a good way to reach Charlotte. The journey takes about 20 hours 25 minutes, and with fares starting at just $152, it presents an excellent value for a comfortable ride.
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Where are the popular stops in St. Louis and Charlotte?
Frequently asked questions about travelling from St. Louis to Charlotte, NC by bus
What is the travel distance from St. Louis to Charlotte?
St. Louis and Charlotte are 914 km (567 miles) apart.
What are the departure and arrival locations for buses traveling from St. Louis to Charlotte?
Buses departing from Gateway Station in St. Louis will take you to Tornado & El Expreso Bus Company in Charlotte.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Charlotte, NC was searched and found on Nov 22, 2025 with a price of $147To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Charlotte, NC, as early as possible.
You can expect to pay from $147 to $330 for a bus ticket from St. Louis to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at $147 which is on 2025-11-22.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from St. Louis to Charlotte, NC?
The bus is the cheapest travel choice for this destination
