Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | Charlotte (Freedom Dr) | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gateway Station | Charlotte Bus Station | No tags | ||||
 | Bus | Gateway Station | Charlotte Bus Station | No tags | ||||
| Bus | Gateway Station | Charlotte Bus Station | No tags | ||||
| Bus | Gateway Station | Charlotte Bus Station | No tags |
Last refresh of the prices: Today at 14:19 CST.
Compare 2 ways to travel from St. Louis to Charlotte
Among the sustainable travel choices, the bus stands out as a good way to reach Charlotte. The journey takes about 20 hours 25 minutes and with fares starting at just £83, it presents an excellent value for a comfortable ride.
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Where are the popular stops in St. Louis and Charlotte?
Frequently asked questions about travelling by bus from St. Louis to Charlotte, NC
How far is Charlotte from St. Louis by coach?
The journey from St. Louis to Charlotte by coach covers an approximate distance of 567 miles (914 km).
Is there a way to reach Charlotte from St. Louis without flying?
To travel from St. Louis to Charlotte without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Charlotte, NC was searched and found on 18 Nov 2025 with a price of £87To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Charlotte, NC as early as possible.
You can expect to pay from £87 to £180 for a bus ticket from St. Louis to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at £91, which is on 2025-11-23.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from St. Louis to Charlotte, NC?
The bus is the cheapest travel choice for this destination
