Bus Tickets from Spartanburg to Chicago

Next bus departures

Next departures for Spartanburg to Chicago on November 19
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Spartanburg
Downtown Greyhound StationCheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Spartanburg
Chicago 95Th & Dan RyanNo tags

Last refresh of the prices: Yesterday at 6:38 PM EST.

Compare 2 ways to go from Spartanburg to Chicago

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 20 hours 30 minutes, and with fares starting at just $170, it presents an excellent value for a comfortable ride.

9bus per day
20h 30mAverage Duration
894 kmDistance
22kgCO₂ emissions
Bus
Average Price$170 - $418Average Duration20h 30m
22kg CO₂e
Train
Average Price$299 - $2,269Average Duration1d 6h
83kg CO₂e

Frequently asked questions about travelling from Spartanburg to Chicago by bus

  1. How far is Spartanburg from Chicago?

    Spartanburg and Chicago are 916 km (568 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Spartanburg to Chicago?

    Buses departing from Super Acapulco in Spartanburg will take you to Downtown Greyhound Station in Chicago.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-17
$226
11-18
No data
Today
$267
11-20
No data
11-21
No data
11-22
No data
11-23
No data
11-24
No data
busbud logoThe cheapest trip from Spartanburg to Chicago was searched and found on Nov 17, 2025 with a price of $226

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Spartanburg to Chicago, as early as possible.

What's the cheapest way to go from Spartanburg to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

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