Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Spartanburg | 537-517 W. Jackson Blvd | No tags | ||||
| Bus | Spartanburg | Downtown Greyhound Station | No tags | ||||
| Bus | Spartanburg | Downtown Greyhound Station | No tags | ||||
| Bus | Spartanburg | 537-517 W. Jackson Blvd | No tags | ||||
FlixBus + Greyhound | Bus | Spartanburg | Chicago 95Th & Dan Ryan | No tags |
Compare 2 ways to go from Spartanburg to Chicago
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 20 hours 30 minutes, and with fares starting at just $171, it presents an excellent value for a comfortable ride.
9bus per day
20h 30mAverage Duration
894 kmDistance
22kgCO₂ emissions
Compare bus companies
US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Where are the popular stops in Spartanburg and Chicago?
Stops in Spartanburg
Stops in Chicago
Frequently asked questions about travelling from Spartanburg to Chicago by bus
How far is Spartanburg from Chicago?
Spartanburg and Chicago are 916 km (568 miles) apart.
What are the departure and arrival locations for buses traveling from Spartanburg to Chicago?
Buses departing from Super Acapulco in Spartanburg will take you to Downtown Greyhound Station in Chicago.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-17
$227
11-18
No data
Today
$267
11-20
No data
11-21
No data
11-22
No data
11-23
No data
11-24
No data
The cheapest trip from Spartanburg to Chicago was searched and found on Nov 17, 2025 with a price of $227To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Spartanburg to Chicago, as early as possible.
What's the cheapest way to go from Spartanburg to Chicago?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
People from around the world trust Busbud
Popular bus departures from Spartanburg
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