Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Spartanburg | Chicago 95Th & Dan Ryan | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Spartanburg | 537-517 W. Jackson Blvd | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Spartanburg | Downtown Greyhound Station | No tags | ||||
 | Bus | Spartanburg | Downtown Greyhound Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Spartanburg | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Yesterday at 03:13 EST.
Compare 2 ways to travel from Spartanburg to Chicago
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 20 hours 30 minutes and with fares starting at just £93, it presents an excellent value for a comfortable ride.
Where are the popular stops in Spartanburg and Chicago?
Stops in Spartanburg
- A9133 Fairforest Rd. Spartanburg, SC , C.P. 29301
- B
Spartanburg Bus Stop
1402 E Main St, Spartanburg, SC 29307, USA - C
Sparta Passenger Center
100 Liberty St, Spartanburg, SC 29306, USA
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Frequently asked questions about travelling by bus from Spartanburg to Chicago
What's the distance between Spartanburg and Chicago by coach?
The journey from Spartanburg to Chicago by coach covers an approximate distance of 568 miles (916 km).
How can I travel from Spartanburg to Chicago avoiding air travel?
To travel from Spartanburg to Chicago without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Spartanburg to Chicago was searched and found on 26 Nov 2025 with a price of £100To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Spartanburg to Chicago as early as possible.
You can expect to pay from £100 to £160 for a bus ticket from Spartanburg to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £100, which is on 2025-11-26.
What's the cheapest way to go from Spartanburg to Chicago?
The bus is the cheapest travel choice for this destination
