Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal de Ómnibus de Santiago del Estero | Mendoza Terminal | Cheapest | ||||
 | Bus | Terminal de Ómnibus de Santiago del Estero | Mendoza Terminal | Fastest |
Last refresh of the prices: Yesterday at 6:38 PM -03.
Get from Santiago del Estero to Mendoza
The journey takes about 17 hours 20 minutes, and with fares starting at just $61, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santiago del Estero and Mendoza?
Stops in Santiago del Estero
- A
Terminal de Ómnibus de Santiago del Estero
Chacabuco, s/n, 4200 Santiago del Estero - BSta Fe 484, 4200 Santiago del Estero, Santiago del Estero, Argentina
Stops in Mendoza
- AAv. Gdor. Ricardo Videla, Mendoza, Argentina
- BAv. Gobernador Ricardo Videla , M5519 Mendoza, Argentina
- CAcceso A Aeropuerto Internacional Gabrielli F. J., Las Heras, Mendoza, Argentina
- DChile 1124, 5500 Mendoza, Argentina
- E
Parada de Autobuses de Mendoza - Nogoli
Nogoli 699, M5501HVC Godoy Cruz, Mendoza, Argentina - F
Vistalba 3020
Vistalba 3020, Godoy Cruz, Mendoza, Argentina
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Frequently asked questions about travelling from Santiago del Estero to Mendoza, AR by bus
What is the distance between Santiago del Estero and Mendoza?
The distance between Santiago del Estero and Mendoza is approximately 717 km (445 miles).
What are the departure and arrival locations for buses traveling from Santiago del Estero to Mendoza?
Buses departing from Terminal de Ómnibus de Santiago del Estero in Santiago del Estero will take you to Mendoza Terminal in Mendoza.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santiago del Estero to Mendoza, AR was searched and found on Nov 26, 2025 with a price of $105To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago del Estero to Mendoza, AR, as early as possible.
You can expect to pay from $105 to $135 for a bus ticket from Santiago del Estero to Mendoza, AR based on the last 2 days. You can expect to find the cheapest price for the trip at $105 which is on 2025-11-26.
Usually Andesmar will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
