Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | San Francisco Bus Station | Pittsburgh Intermodal Station | CheapestFastest | |||||
 | Mission St & Fremont St | Union Station | No tags | |||||
| San Francisco Bus Station | Pittsburgh Intermodal Station | No tags | |||||
| Mission St & Fremont St | Union Station | No tags |
Last refresh of the prices: Yesterday at 5:28 AM PST.
Get from San Francisco to Pittsburgh
The journey takes about 2 days, 16 hours 30 minutes, and with fares starting at just $274, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Francisco and Pittsburgh?
Stops in San Francisco
- A
Hyde/Beach (Fisherman's Wharf)
700 Beach Street, San Francisco, CA 94109, USA - B
Powell Station
25 Cyril Magnin St , San Francisco, CA 94102-2812 - C
Union Square Hilton
255 Mason St,, San Francisco, CA 94102-2114 - D
San Francisco Greyhound Station
200 Folsom St, San Francisco, CA 94105 - E
444 Townsend St.
444 Townsend St, San Francisco, CA 94107, USA
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
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Frequently asked questions about travelling from San Francisco, US to Pittsburgh by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Francisco to Pittsburgh?
The cheapest bus tickets from San Francisco to Pittsburgh start from $274. The average price for this route is around $554. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Francisco to Pittsburgh?
The average bus travel time from San Francisco to Pittsburgh is 2d 16h, covering a distance of 3636 km. The quickest bus can get you there in 2d 11h and is operated by Greyhound.
Which bus companies service the San Francisco to Pittsburgh route?
What are the earliest and latest departure times for the bus from San Francisco to Pittsburgh?
The earliest bus departs from San Francisco to Pittsburgh at 8:20am. And the latest bus departs at 10:40pm.
What are the CO₂ emissions for the bus trip from San Francisco to Pittsburgh?
A bus trip from San Francisco to Pittsburgh generates an estimated 91 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from San Francisco to Pittsburgh?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5733 reviews.
Which bus company has the best Wi-Fi from San Francisco to Pittsburgh?
Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from San Francisco to Pittsburgh?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Francisco to Pittsburgh?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Francisco, US to Pittsburgh was searched and found on Jan 21, 2026 with a price of $264To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to Pittsburgh, as early as possible.
You can expect to pay from $264 to $1,766 for a bus ticket from San Francisco, US to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at $264 which is on 2026-01-21.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
