Based on 11380 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $61
Based on 87383 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $73
Florida's Turnpike, Milepost 144, Port St Lucie, FL 34984, USA
D - Port Saint Lucie Bus Stop
2198 SW Gatlin Blvd. Port St. Lucie, FL 34953
Stops in Tampa
A - Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605
B - Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA
C - Greyhound Station
610 E Polk St, Tampa, FL 33602, USA
D - E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA
E - N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA
F - Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Frequently asked questions about travelling from Port Saint Lucie to Tampa by bus
What is the travel distance from Port Saint Lucie to Tampa?
Port Saint Lucie and Tampa are 221 km (137 miles) apart.
What are the departure and arrival locations for buses traveling from Port Saint Lucie to Tampa?
Buses departing from Port St Lucie Mobil Gas Bus Stop in Port Saint Lucie will take you to Tampa 13th Avenue Bus Stop (McDonald's) in Tampa.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-18
$74
11-19
$68
Today
$74
11-21
$74
11-22
$74
11-23
$81
11-24
$74
11-25
$77
The cheapest trip from Port Saint Lucie to Tampa was searched and found on Nov 19, 2025 with a price of $68
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Port Saint Lucie to Tampa, as early as possible.
You can expect to pay from $68 to $103 for a bus ticket from Port Saint Lucie to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $74 which is on 2025-11-21.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Port Saint Lucie to Tampa was searched and found on Nov 19, 2025 with a price of $68
