What is the distance between Philadelphia and Greenville?

The distance between Philadelphia and Greenville is around 855 km (530 miles).

What are the departure and arrival locations for buses traveling from Philadelphia to Greenville?

Buses traveling this route start their trip at Philadelphia Airport, in Philadelphia, and end it at Guadalajara Supermarket Bus Stop, in Greenville.

Bus Philadelphia to Greenville from $105 | Refundable Tickets

Next bus departures

Next departures for Philadelphia to Greenville on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	5:50pm	199 Spring Garden St.	17h	10:50am	1116 Woodruff Rd	Cheapest
	Bus	6:30pm	Philadelphia, 199 Spring Garden St	14h 5m	8:35am	1116 Woodruff Rd	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	3:20pm	199 Spring Garden St.	17h 15m	8:35am	1116 Woodruff Rd	No tags
	Bus	10:00pm	Philadelphia, 199 Spring Garden St	15h 15m	1:15pm	1116 Woodruff Rd	No tags
	Bus	8:00pm	Schuylkill & Walnut	18h 35m	2:35pm	1116 Woodruff Rd	No tags

Last refresh of the prices: Last Saturday at 2:53 PM EST.

Compare 2 ways to go from Philadelphia to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 18 hours 35 minutes, and with fares starting at just $116, it presents an excellent value for a comfortable ride.

19bus per day

18h 35mAverage Duration

850 kmDistance

21kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$116 - $475	Average Duration18h 35m	CO₂ emissions 21kg CO₂e
Train	Average Price$185 - $389	Average Duration13h 46m	CO₂ emissions 78kg CO₂e

Where are the popular stops in Philadelphia and Greenville?

Stops in Philadelphia

A
Philadelphia Airport
Visit page
B
Independence Travel Center
Off of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
Visit page
C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA
D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA
E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA
F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA

Stops in Greenville

A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611
B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607

Compare bus companies

FlixBus

3.5/511,440 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Greyhound

3.5/587,394 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Philadelphia, PA to Greenville, SC by bus

What is the distance between Philadelphia and Greenville?
The distance between Philadelphia and Greenville is around 855 km (530 miles).
What are the departure and arrival locations for buses traveling from Philadelphia to Greenville?
Buses traveling this route start their trip at Philadelphia Airport, in Philadelphia, and end it at Guadalajara Supermarket Bus Stop, in Greenville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-23

$150

11-24

$215

Today

$309

11-26

$196

11-27

$147

11-28

No data

11-29

No data

11-30

$257

The cheapest trip from Philadelphia, PA to Greenville, SC was searched and found on Nov 27, 2025 with a price of $147

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Greenville, SC, as early as possible.

You can expect to pay from $147 to $469 for a bus ticket from Philadelphia, PA to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $147 which is on 2025-11-27.