Cheap buses leaving Saturday
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: June 21 atDeparture city: New CastleDeparture location: Route 422 Park & RideArrival time: June 22 atDestination city: St LouisDestination location: Gateway StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Last Saturday at 9:38 AM EDT.
Prices and availability are subject to change.
Accepted payments
Bus New Castle to St Louis: Trip Overview
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Based on 87042 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at US$114.00
New Castle to St Louis Bus
With Busbud, comparing and booking tickets for a bus from New Castle to St Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from New Castle to St Louis will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from New Castle to St Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Frequently asked questions on the trip New Castle - St Louis
How long is the trip from New Castle to St Louis by bus?
The trip from New Castle to St Louis will take on average 16h 25m. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 16h 25m.
What is the travel distance from New Castle to St Louis?
It's about 888 km (551 miles) from New Castle to St Louis.
What is the cheapest way to travel from New Castle to St Louis?
If you're on a budget, consider traveling by bus to St Louis from New Castle; it tends to be more affordable. The ticket price for this bus starts at US$2, making this your best choice for this trip.
How much does the bus ticket cost from New Castle to St Louis?
Taking the bus from New Castle to St Louis costs on average US$2.
Is there an overnight bus from New Castle to St Louis?
Yes! Catch buses leaving from New Castle until 3:00pm and reaching St Louis on the following day.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from New Castle to St Louis was searched and found on Jun 21, 2025 with a price of US$120To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Castle to St Louis, as early as possible.
You can expect to pay from US$120 to US$120 for a bus ticket from New Castle to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$120 which is on 2025-06-21.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from New Castle to St Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from New Castle to St Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from New Castle to St Louis that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from New Castle to St Louis while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top travelled bus routes
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