Bus Tickets from Lakeland, FL to Charleston, SC, US
Next departures
Next departures for Lakeland to Charleston on November 25
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Recommended
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FlixBus + Greyhound Lines, Inc.
Lakeland
4565 Gaynor Ave, North Charleston
CheapestFastest
Next departures for Lakeland to Charleston on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Lakeland
4565 Gaynor Ave, North Charleston
Cheapest
Lakeland Station
Charleston Station
Fastest
Lakeland Station
Charleston Station
No tags
Next departures for Lakeland to Charleston on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Lakeland Station
Charleston Station
CheapestFastest
Lakeland Station
Charleston Station
No tags
FlixBus + Greyhound Lines, Inc.
Lakeland
4565 Gaynor Ave, North Charleston
No tags
Last refresh of the prices: Last Friday at 12:25 PM EST.
Compare 2 ways to go from Lakeland to Charleston
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Charleston. The journey takes about 19 hours 5 minutes, and with fares starting at just $74, it presents an excellent value for a comfortable ride.
Based on 11440 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at $94
Based on 5607 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $116
Based on 87394 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $104
Frequently asked questions about travelling from Lakeland, FL to Charleston, SC, US by bus
What is the travel distance from Lakeland to Charleston?
The distance between Lakeland and Charleston is around 563 km (349 miles).
What are the departure and arrival locations for buses traveling from Lakeland to Charleston?
Buses traveling this route start their trip at Lakeland Bus Stop (McDonald's), in Lakeland, and end it at Charleston Bus Station, in Charleston.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-23
$242
11-24
$242
Today
$199
11-26
$242
11-27
No data
11-28
$135
11-29
No data
11-30
No data
The cheapest trip from Lakeland, FL to Charleston, SC, US was searched and found on Nov 28, 2025 with a price of $135
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lakeland, FL to Charleston, SC, US, as early as possible.
You can expect to pay from $135 to $872 for a bus ticket from Lakeland, FL to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $135 which is on 2025-11-28.
What's the cheapest way to go from Lakeland, FL to Charleston, SC, US?
The bus is the cheapest travel choice for this destination
The cheapest trip from Lakeland, FL to Charleston, SC, US was searched and found on Nov 28, 2025 with a price of $135
The bus is the cheapest travel choice for this destination
