Bus from Indianapolis to Des Moines: Tickets & Schedules

Previously seen trips

Next departures for Indianapolis to Des Moines on November 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
GreyhoundBus
Indianapolis Bus Station
Des Moines (Subway)No tags
FlixBus + Greyhound
Bus
Downtown Transit Center
Des Moines (Subway)No tags
GreyhoundBus
Indianapolis Bus Station
Des Moines (Subway)No tags
GreyhoundBus
Indianapolis Bus Station
Des Moines (Subway)No tags
Greyhound + FlixBus
Bus
Downtown Transit Center
Des Moines (Subway)No tags

Get from Indianapolis to Des Moines

This route is served by bus only

The journey takes about 15 hours 45 minutes, and with fares starting at just $103, it presents an excellent value for a comfortable ride.

3bus per day
15h 45mAverage Duration
660 kmDistance
16kgCO₂ emissions

Frequently asked questions about travelling from Indianapolis to Des Moines by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Indianapolis to Des Moines?

    The cheapest bus tickets from Indianapolis to Des Moines start from $103. The average price for this route is around $158. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Indianapolis to Des Moines?

    The average bus travel time from Indianapolis to Des Moines is 15h 45m, covering a distance of 660 km. The quickest bus can get you there in 12h and is operated by Burlington Trailways.

  3. Which bus companies service the Indianapolis to Des Moines route?

    Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, Burlington Trailways, FlixBus.

  4. What are the earliest and latest departure times for the bus from Indianapolis to Des Moines?

    The earliest bus departs from Indianapolis to Des Moines at 12:05am. And the latest bus departs at 11:15pm.

  5. What are the CO₂ emissions for the bus trip from Indianapolis to Des Moines?

    A bus trip from Indianapolis to Des Moines generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Indianapolis to Des Moines?

    According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.

  7. Which bus company has the best Wi-Fi from Indianapolis to Des Moines?

    Based on Busbud reviews, the bus company Burlington Trailways has the highest Wi-Fi rating with a score of 5.0.

  8. Which bus company has the best on-time performance from Indianapolis to Des Moines?

    According to Busbud traveller reviews, the most punctual bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Indianapolis to Des Moines?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-26
$321
11-27
$181
Today
$164
11-29
$178
11-30
$270
12-01
$190
12-02
$128
12-03
$113
busbud logoThe cheapest trip from Indianapolis to Des Moines was searched and found on Dec 3, 2025 with a price of $113

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Des Moines, as early as possible.

You can expect to pay from $113 to $371 for a bus ticket from Indianapolis to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $113 which is on 2025-12-03.

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