Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Ft Myers Bus Station | Charlotte (Freedom Dr) | Cheapest | |||||
FlixBus + Greyhound Lines, Inc. | Ft Myers Bus Station | Charlotte Bus Station | Fastest | |||||
 | Love's Travel Stop | Amtrak Station | No tags | |||||
 | Ft Myers Bus Station | Charlotte Bus Station | No tags | |||||
| Love's Travel Stop | Amtrak Station | No tags |
Last refresh of the prices: Last Wednesday at 4:11 AM EST.
Get from Fort Myers to Charlotte
The journey takes about 22 hours 15 minutes, and with fares starting at just $175, it presents an excellent value for a comfortable ride.
Where are the popular stops in Fort Myers and Charlotte?
Stops in Fort Myers
Stops in Charlotte
- A
Tornado & El Expreso Bus Company
4705 N. Tryon S, Charlotte, NC, USA - C
Charlotte Greyhound Bus Station
601 W Trade St , Charlotte, NC 28202 - D
Agencia El Salvador Bus Stop
4335 N Tryon St, Charlotte, NC 28213 - E
4127 Glenwood Dr
4127 Glenwood Dr, Charlotte, NC 28208 (Exxon Gas Station)
Compare bus companies
Frequently asked questions about travelling from Fort Myers to Charlotte, NC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Fort Myers to Charlotte?
The cheapest bus tickets from Fort Myers to Charlotte start from $175. The average price for this route is around $228. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Fort Myers to Charlotte?
The average bus travel time from Fort Myers to Charlotte is 22h 15m, covering a distance of 961 km. The quickest bus can get you there in 22h 15m and is operated by FlixBus.
Which bus companies service the Fort Myers to Charlotte route?
What are the earliest and latest departure times for the bus from Fort Myers to Charlotte?
The earliest bus departs from Fort Myers to Charlotte at 10:45am. And the latest bus departs at 6:30pm.
What are the CO₂ emissions for the bus trip from Fort Myers to Charlotte?
A bus trip from Fort Myers to Charlotte generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Fort Myers to Charlotte?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5696 reviews.
Which bus company has the best Wi-Fi from Fort Myers to Charlotte?
Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Fort Myers to Charlotte?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Fort Myers to Charlotte?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Fort Myers to Charlotte, NC was searched and found on Jan 11, 2026 with a price of $208To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Fort Myers to Charlotte, NC, as early as possible.
You can expect to pay from $208 to $1,774 for a bus ticket from Fort Myers to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at $208 which is on 2026-01-11.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
