What is the travel distance from Detroit to Syracuse?

The distance between Detroit and Syracuse is around 570 km (354 miles).

What are the departure and arrival locations for buses traveling from Detroit to Syracuse?

Buses traveling this route start their trip at Detroit Bus Station, in Detroit, and end it at Regional Transportation Center, in Syracuse.

Bus Detroit to Syracuse from $318 | Refundable Tickets

Next departures

Next departures for Detroit to Syracuse on November 24
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
9:30pm	Amtrak Station	13h 58m	11:28am	Amtrak Station	CheapestFastest
9:30pm	Amtrak Station	18h 15m	3:45pm	SYR Airport	No tags
9:30pm	Amtrak Station	18h 15m	3:45pm	SYR Airport	No tags
9:30pm	Amtrak Station	13h 58m	11:28am	Amtrak Station	No tags

Last refresh of the prices: Yesterday at 3:38 PM EST.

Compare 2 ways to go from Detroit to Syracuse

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 13 hours 20 minutes, and with fares starting at just $111, it presents an excellent value for a comfortable ride.

1bus per day

13h 20mAverage Duration

569 kmDistance

14kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$111 - $113	Average Duration13h 20m	CO₂ emissions 14kg CO₂e
Train	Average Price$250 - $298	Average Duration1d 1h	CO₂ emissions 52kg CO₂e

Where are the popular stops in Detroit and Syracuse?

Stops in Detroit

A
Detroit Bus Station
1001 Howard St, Detroit, MI 48226, USA
Visit page

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Compare bus companies

Amtrak

4/55,597 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Greyhound

3.5/587,388 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Detroit, MI to Syracuse, US by bus

What is the travel distance from Detroit to Syracuse?
The distance between Detroit and Syracuse is around 570 km (354 miles).
What are the departure and arrival locations for buses traveling from Detroit to Syracuse?
Buses traveling this route start their trip at Detroit Bus Station, in Detroit, and end it at Regional Transportation Center, in Syracuse.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-19

No data

11-20

$106

Today

No data

11-22

No data

11-23

No data

11-24

$318

11-25

No data

11-26

No data

The cheapest trip from Detroit, MI to Syracuse, US was searched and found on Nov 20, 2025 with a price of $106

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Syracuse, US, as early as possible.

You can expect to pay from $106 to $1,741 for a bus ticket from Detroit, MI to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $318 which is on 2025-11-24.