What is the distance between Detroit and St. Louis?

The distance covered from Detroit to St. Louis is 733 km (454 miles).

What are the departure and arrival locations for buses traveling from Detroit to St. Louis?

Buses traveling this route start their trip at Detroit Bus Station, in Detroit, and end it at Gateway Station, in St. Louis.

Bus Detroit to St. Louis from $96 | Refundable Tickets

Next bus departures

Next departures for Detroit to St. Louis on November 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	11:25pm	Detroit Bus Station	16h 55m	3:20pm	Gateway Station	CheapestFastest

Next departures for Detroit to St. Louis on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	8:20am	Detroit Bus Station	15h 50m	11:10pm	Gateway Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	4:20pm	Detroit Bus Station	15h 5m	6:25am	Gateway Station	Fastest
	Bus	11:25pm	Detroit Bus Station	16h 55m	3:20pm	Gateway Station	No tags

Next departures for Detroit to St. Louis on November 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	6:40am	Detroit Bus Station	17h 45m	11:25pm	Gateway Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	4:20pm	Detroit Bus Station	15h 5m	6:25am	Gateway Station	Fastest
	Bus	11:25pm	Detroit Bus Station	16h 55m	3:20pm	Gateway Station	No tags

Next departures for Detroit to St. Louis on November 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	6:40am	Detroit Bus Station	17h 45m	11:25pm	Gateway Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	4:20pm	Detroit Bus Station	15h 5m	6:25am	Gateway Station	Fastest
	Bus	11:25pm	Detroit Bus Station	16h 55m	3:20pm	Gateway Station	No tags

Next departures for Detroit to St. Louis on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	8:20am	Detroit Bus Station	15h 50m	11:10pm	Gateway Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	4:20pm	Detroit Bus Station	15h 5m	6:25am	Gateway Station	Fastest
	Bus	11:25pm	Detroit Bus Station	16h 55m	3:20pm	Gateway Station	No tags

Next departures for Detroit to St. Louis on November 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	8:20am	Detroit Bus Station	15h 50m	11:10pm	Gateway Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	4:20pm	Detroit Bus Station	15h 5m	6:25am	Gateway Station	Fastest
	Bus	11:25pm	Detroit Bus Station	16h 55m	3:20pm	Gateway Station	No tags

Last refresh of the prices: Yesterday at 5:36 PM EST.

Compare 2 ways to go from Detroit to St. Louis

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 13 hours 41 minutes, and with fares starting at just $109, it presents an excellent value for a comfortable ride.

1train per day

13h 41mAverage Duration

733 kmDistance

67kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$102 - $346	Average Duration15h 50m	CO₂ emissions 18kg CO₂e
Train	Average Price$109 - $685	Average Duration13h 41m	CO₂ emissions 67kg CO₂e

Where are the popular stops in Detroit and St. Louis?

Stops in Detroit

A
Detroit Bus Station
1001 Howard St, Detroit, MI 48226, USA
Visit page

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

Greyhound

3.5/587,393 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/511,432 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Detroit, MI to St. Louis by bus

What is the distance between Detroit and St. Louis?
The distance covered from Detroit to St. Louis is 733 km (454 miles).
What are the departure and arrival locations for buses traveling from Detroit to St. Louis?
Buses traveling this route start their trip at Detroit Bus Station, in Detroit, and end it at Gateway Station, in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-22

$200

11-23

$222

Today

$264

11-25

$418

11-26

$200

11-27

$122

11-28

$157

11-29

$294

The cheapest trip from Detroit, MI to St. Louis was searched and found on Nov 27, 2025 with a price of $122

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to St. Louis, as early as possible.

You can expect to pay from $122 to $418 for a bus ticket from Detroit, MI to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $122 which is on 2025-11-27.