Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Amtrak Station | Depew Station | CheapestFastest | |||||
| Amtrak Station | Depew Station | No tags |
Last refresh of the prices: Last Monday at 10:48 PM EST.
Compare 2 ways to go from Detroit to Buffalo
Among the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 8 hours 40 minutes, and with fares starting at just $59, it presents an excellent value for a comfortable ride.
Where are the popular stops in Detroit and Buffalo?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Compare bus companies
Frequently asked questions about travelling from Detroit, MI to Buffalo, NY by bus
What is the travel distance from Detroit to Buffalo?
The distance covered from Detroit to Buffalo is 347 km (216 miles).
What are the departure and arrival locations for buses traveling from Detroit to Buffalo?
Buses traveling this route start their trip at Detroit Bus Station, in Detroit, and end it at Buffalo Airport, in Buffalo.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Buffalo, NY was searched and found on Nov 19, 2025 with a price of $133To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Buffalo, NY, as early as possible.
You can expect to pay from $133 to $668 for a bus ticket from Detroit, MI to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $133 which is on 2025-11-26.
What's the cheapest way to go from Detroit, MI to Buffalo, NY?
The bus is the cheapest travel choice for this destination
