Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | DENVER | San Antonio Bus Station | CheapestFastest |
Last refresh of the prices: Today at 11:49 AM MST.
Get from Denver to San Antonio
The journey takes about 21 hours 20 minutes, and with fares starting at just $175, it presents an excellent value for a comfortable ride.
Where are the popular stops in Denver and San Antonio?
Stops in Denver
- A1701 Wynkoop St, Denver, CO 80202
- B
Bus Station
1055 19th St, Denver, CO 80202
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C165 Bowie St, San Antonio, 78205
- D4407 S PanAm Expy #101, San Antonio, TX 78225, USA
Compare bus companies
Based on 87397 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $175
Greyhound Denver San Antonio recent customer reviews
It delay the bus one day I couldn’t get my bus on the same day I was supposed to leave
Sergio G.
I was not told that I had to leave immediately and bus left without me in Amarillo. I had to wait for another bus and take a detour thru Dallas when I paid for a direct route ticket to Denver to San Antonio. It was a lot longer and no one seemed to care to communicate with me.
Austin F.
Bus driver was perfect as for as staff working there well it was very poor
Adam Jr. C.
Frequently asked questions about travelling from Denver to San Antonio, US by bus
How far is Denver from San Antonio?
Denver and San Antonio are 1293 km (802 miles) apart.
What are the departure and arrival locations for buses traveling from Denver to San Antonio?
Buses departing from Union Station in Denver will take you to San Antonio Bus Station in San Antonio.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Denver to San Antonio, US was searched and found on Nov 28, 2025 with a price of $261To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Denver to San Antonio, US, as early as possible.
You can expect to pay from $261 to $468 for a bus ticket from Denver to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at $261 which is on 2025-11-28.
