Bus Tickets from Chicago to Florence (SC), US

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TodayJun 11
TomorrowJun 12
FriJun 13
from US$162
SatJun 14
from US$119
SunJun 15
MonJun 16
from US$173
TueJun 17
WedJun 18

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 13 at
    Departure city: Chicago
    Departure location: Chicago 95Th & Dan Ryan
    Arrival time: June 14 at
    Destination city: Florence
    Destination location: Bus station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: June 13 at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: June 14 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 13 at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: June 15 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: June 13 at
    Departure city: Chicago
    Departure location: 537-517 W. Jackson Blvd
    Arrival time: June 15 at
    Destination city: Florence
    Destination location: Bus station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: June 13 at
    Departure city: Chicago
    Departure location: 537-517 W. Jackson Blvd
    Arrival time: June 14 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Thursday at 7:50 PM CDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from Chicago to Florence

Average PriceUS$115 - US$281Average Duration1d 6h
27kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$344 - US$512Average Duration1d 7h
100kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Chicago to Florence

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 1 day, 6 hours 30 minutes, and with fares starting at just US$115, it presents an excellent value for a comfortable ride.

6.4bus per day
1d 6hAverage Duration
US$115Cheapest ticket
27kgCO₂ emissions

Bus Chicago to Florence: Trip Overview

Average Ticket PriceUS$179
Average Bus Trip Duration1d 6h
Number of daily buses6
Earliest bus departure10:00am
Distance1083 km
Latest bus departure11:15pm

Chicago to Florence Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Chicago to Florence.

Bus service from Chicago to Florence will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Florence from Chicago, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Chicago - Florence (SC), US

  1. How long is the bus trip from Chicago to Florence?

    The trip from Chicago to Florence will take on average 1d 6h. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 1d 1h.

  2. How far is Chicago from Florence?

    The distance covered from Chicago to Florence is 1102 km (684 miles).

  3. What are the departure and arrival locations for buses traveling from Chicago to Florence?

    Buses traveling this route start their trip at Downtown Greyhound Station, in Chicago, and end it at Florence Bus Station, in Florence.

  4. What is the cheapest way to go from Chicago to Florence?

    If you're on a budget, consider traveling by bus to Florence from Chicago; it tends to be more affordable. With a starting ticket price of US$115, this bus becomes your top pick for this journey.

  5. How much does it cost to take the bus from Chicago to Florence?

    The bus fare from Chicago to Florence is approximately US$179.

  6. Can I take an overnight bus from Chicago to Florence?

    Yes! Catch buses leaving from Chicago until 11:15pm and reaching Florence on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-09
No data
06-10
No data
Today
No data
06-12
No data
06-13
US$154
06-14
US$154
06-15
No data
06-16
No data
busbud logoThe cheapest trip from Chicago to Florence was searched and found on Jun 13, 2025 with a price of US$154

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Florence, as early as possible.

You can expect to pay from US$154 to US$154 for a bus ticket from Chicago to Florence based on the last 2 days. You can expect to find the cheapest price for the trip at US$154 which is on 2025-06-13.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Chicago to Florence but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Chicago to Florence, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Chicago to Florence.

Make a music playlist for your bus ride from Chicago to Florence, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Chicago to Florence?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Chicago by bus?

Bus from Chicago to Florence

You can also go to Florence by train

Train from Chicago to Florence

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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