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- This trip is recommended because it is the: Cheapest + Fastest
Last refresh of the prices: Last Monday at 10:30 AM CDT.
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Compare 2 ways to go from Chicago to Florence
Busbud recommends taking the bus from Chicago to FlorenceAmong the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 1 day, 6 hours 30 minutes, and with fares starting at just US$115, it presents an excellent value for a comfortable ride.
Bus Chicago to Florence: Trip Overview
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Chicago to Florence Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Chicago to Florence.
Bus service from Chicago to Florence will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Florence from Chicago, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Chicago and Florence?
Frequently asked questions on the trip Chicago - Florence (SC), US
How long is the bus trip from Chicago to Florence?
The trip from Chicago to Florence will take on average 1d 6h. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 1d 1h.
How far is Chicago from Florence?
The distance covered from Chicago to Florence is 1102 km (684 miles).
What are the departure and arrival locations for buses traveling from Chicago to Florence?
Buses traveling this route start their trip at Downtown Greyhound Station, in Chicago, and end it at Florence Bus Station, in Florence.
What is the cheapest way to go from Chicago to Florence?
If you're on a budget, consider traveling by bus to Florence from Chicago; it tends to be more affordable. With a starting ticket price of US$115, this bus becomes your top pick for this journey.
How much does it cost to take the bus from Chicago to Florence?
The bus fare from Chicago to Florence is approximately US$179.
Can I take an overnight bus from Chicago to Florence?
Yes! Catch buses leaving from Chicago until 11:15pm and reaching Florence on the following day.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Florence was searched and found on Jun 13, 2025 with a price of US$154To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Florence, as early as possible.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Chicago to Florence but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from Chicago to Florence, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Chicago to Florence.
Make a music playlist for your bus ride from Chicago to Florence, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
What's the cheapest way to go from Chicago to Florence?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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