Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Charlotte Bus Station | Gateway Station | Cheapest | ||||
 | Bus | Charlotte Bus Station | Gateway Station | Fastest | ||||
 | Bus | Charlotte Bus Station | Gateway Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Charlotte Bus Station | Gateway Station | No tags | ||||
| Bus | Charlotte Bus Station | Gateway Station | No tags |
Last refresh of the prices: Last Friday at 6:23 PM EST.
Get from Charlotte to St. Louis
The journey takes about 23 hours 5 minutes, and with fares starting at just $106, it presents an excellent value for a comfortable ride.
Where are the popular stops in Charlotte and St. Louis?
Stops in Charlotte
- A
Tornado & El Expreso Bus Company
4705 N. Tryon S, Charlotte, NC, USA - C
Charlotte Greyhound Bus Station
601 W Trade St , Charlotte, NC 28202 - D
Agencia El Salvador Bus Stop
4335 N Tryon St, Charlotte, NC 28213 - E
4127 Glenwood Dr
4127 Glenwood Dr, Charlotte, NC 28208 (Exxon Gas Station)
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Frequently asked questions about travelling from Charlotte, NC to St. Louis by bus
What is the distance between Charlotte and St. Louis?
Charlotte and St. Louis are 914 km (567 miles) apart.
What are the departure and arrival locations for buses traveling from Charlotte to St. Louis?
Buses departing from Tornado & El Expreso Bus Company in Charlotte will take you to Gateway Station in St. Louis.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charlotte, NC to St. Louis was searched and found on Nov 24, 2025 with a price of $203To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlotte, NC to St. Louis, as early as possible.
You can expect to pay from $203 to $352 for a bus ticket from Charlotte, NC to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $210 which is on 2025-11-29.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
