Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Charlotte Bus Station | Gateway Station | Cheapest | ||||
 | Bus | Charlotte Bus Station | Gateway Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Charlotte Bus Station | Gateway Station | No tags | ||||
| Bus | Charlotte Bus Station | Gateway Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Charlotte (Freedom Dr) | Gateway Station | No tags |
Last refresh of the prices: Last Friday at 18:23 EST.
Get from Charlotte to St. Louis
The journey takes about 23 hours 5 minutes, and with fares starting at just £65, it presents an excellent value for a comfortable ride.
Where are the popular stops in Charlotte and St. Louis?
Stops in Charlotte
- A
Tornado & El Expreso Bus Company
4705 N. Tryon S, Charlotte, NC, USA - C
Charlotte Greyhound Bus Station
601 W Trade St , Charlotte, NC 28202 - D
Agencia El Salvador Bus Stop
4335 N Tryon St, Charlotte, NC 28213 - E
4127 Glenwood Dr
4127 Glenwood Dr, Charlotte, NC 28208 (Exxon Gas Station)
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Frequently asked questions about travelling by bus from Charlotte, NC to St. Louis
What's the distance between Charlotte and St. Louis by coach?
The journey from Charlotte to St. Louis by coach covers an approximate distance of 567 miles (914 km).
What is the best way to go from Charlotte to St. Louis without flying?
To travel from Charlotte to St. Louis without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charlotte, NC to St. Louis was searched and found on 24 Nov 2025 with a price of £110To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charlotte, NC to St. Louis as early as possible.
You can expect to pay from £110 to £190 for a bus ticket from Charlotte, NC to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at £114, which is on 2025-11-29.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
Top travelled bus routes
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