Next departures for Prague to Frankfurt am Main on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
EuroCity Train + Deutsche Bahn ICE
Hlavní nádraží
Frankfurt Hbf
CheapestFastest
EuroCity Train + Deutsche Bahn ICE + S-Bahn
Hlavní nádraží
Frankfurt Süd
No tags
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Süd
No tags
EuroCity Train + Deutsche Bahn ICE
Hlavní nádraží
Frankfurt Hbf
No tags
EuroCity Train + Deutsche Bahn ICE + S-Bahn
Hlavní nádraží
Frankfurt Süd
No tags
Next departures for Prague to Frankfurt am Main on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
EuroCity Train + Deutsche Bahn ICE
Hlavní nádraží
Frankfurt Hbf
CheapestFastest
EuroCity Train + Deutsche Bahn ICE
Hlavní nádraží
Frankfurt am Main Frankfurt West
No tags
EuroCity Train + Deutsche Bahn ICE + S-Bahn
Hlavní nádraží
Frankfurt Süd
No tags
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Süd
No tags
EuroCity Train + Deutsche Bahn ICE
Hlavní nádraží
Frankfurt am Main Frankfurt West
No tags
Next departures for Prague to Frankfurt am Main on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Flixbus + Flixtrain
PRG Airport
Südbahnhof
Cheapest
EuroCity Train + Deutsche Bahn ICE
Hlavní nádraží
Frankfurt Hbf
Fastest
EuroCity Train + Deutsche Bahn ICE
Hlavní nádraží
Frankfurt am Main Frankfurt West
No tags
EuroCity Train + Deutsche Bahn ICE + S-Bahn
Hlavní nádraží
Frankfurt Süd
No tags
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Süd
No tags
Next departures for Prague to Frankfurt am Main on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Flixbus + Flixtrain
PRG Airport
Südbahnhof
Cheapest
EuroCity Train + Deutsche Bahn ICE
Hlavní nádraží
Frankfurt Hbf
Fastest
EuroCity Train + Deutsche Bahn ICE
Hlavní nádraží
Frankfurt am Main Frankfurt West
No tags
EuroCity Train + Deutsche Bahn ICE + Regional-Express
Hlavní nádraží
Frankfurt Süd
No tags
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Süd
No tags
Next departures for Prague to Frankfurt am Main on November 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Flixbus + Flixtrain
PRG Airport
Südbahnhof
Cheapest
EuroCity Train + InterCity + Deutsche Bahn ICE
Hlavní nádraží
Frankfurt Hbf
Fastest
Flixbus + Flixtrain
Prague (Central Bus Station Florenc)
Südbahnhof
No tags
EuroCity Train + InterCity + Deutsche Bahn ICE + S-Bahn
Hlavní nádraží
Frankfurt am Main Frankfurt West
No tags
InterCity + Regional-Express + S-Bahn
Hlavní nádraží
Frankfurt am Main Frankfurt West
No tags
Next departures for Prague to Frankfurt am Main on November 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Flixbus + Flixtrain
PRG Airport
Südbahnhof
Cheapest
EuroCity Train + InterCity + Deutsche Bahn ICE
Hlavní nádraží
Frankfurt Hbf
Fastest
Flixbus + Flixtrain
Prague (Central Bus Station Florenc)
Südbahnhof
No tags
EuroCity Train + InterCity + Deutsche Bahn ICE + S-Bahn
Hlavní nádraží
Frankfurt am Main Frankfurt West
No tags
InterCity + Regional-Express + S-Bahn
Hlavní nádraží
Frankfurt am Main Frankfurt West
No tags
Next departures for Prague to Frankfurt am Main on December 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Süd
CheapestFastest
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Süd
No tags
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Hbf
No tags
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Hbf
No tags
InterCity + Regional-Express + S-Bahn
Hlavní nádraží
Frankfurt am Main Frankfurt West
No tags
Next departures for Prague to Frankfurt am Main on December 2
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Süd
CheapestFastest
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Süd
No tags
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Hbf
No tags
InterCity + Regional-Express
Hlavní nádraží
Frankfurt Hbf
No tags
InterCity + Regional-Express + S-Bahn
Hlavní nádraží
Frankfurt am Main Frankfurt West
No tags
Last refresh of the prices: Today at 6:11 AM CET.
Compare 3 ways to go from Prague to Frankfurt am Main
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Frankfurt am Main. The journey takes about 5 hours 10 minutes and with fares starting at just $24, it presents an excellent value for a comfortable ride.
Based on 6 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the power outlets and the ticket access but often complained with the timeliness. Deutsche Bahn ticket prices on this trip start at $38
Based on 1 reviews, the company was rated 5 stars on Busbud. Travelers were especially satisfied with the staff and the timeliness but often complained with the ticket access. Deutsche Bahn EuroCity ticket prices on this trip start at $32
Frequently asked questions about traveling from Prague to Frankfurt am Main by train
How much does a train ticket from Prague to Frankfurt am Main cost?
The average train ticket price from Prague to Frankfurt am Main is $126. The best way to find train tickets from Prague to Frankfurt am Main is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Prague to Frankfurt am Main?
A train trip between Prague and Frankfurt am Main is around 8h 27m, although the fastest train will take about 7h 1m. This is the time it takes to travel the 254 miles that separates the two cities.
How many daily trains are there between Prague and Frankfurt am Main?
The number of trains from Prague to Frankfurt am Main can differ depending on the day of the week. On average, there are 17. Some trains are direct while others have layovers. Simplify your train trip from Prague to Frankfurt am Main by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Prague to Frankfurt am Main?
When taking the train from Prague to Frankfurt am Main, you can travel comfortably and safely with Deutsche Bahn, Deutsche Bahn EuroCity.
What are the departure and arrival stations for a train from Prague to Frankfurt am Main?
Trains traveling between Prague and Frankfurt am Main leave from Hlavní nádraží or Florenc and arrive at Südbahnhof, Frankfurt Airport.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/23
No data
11/24
$30
Today
$36
11/26
$36
11/27
$42
11/28
$48
11/29
$36
11/30
$51
The cheapest trip from Prague to Frankfurt am Main was searched and found on Nov 24, 2025 with a price of $30
To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Prague to Frankfurt am Main, as early as possible.
You can expect to pay from $30 to $282 for a train ticket from Prague to Frankfurt am Main based on the last 2 days. You can expect to find the cheapest price for the trip at $36 which is on 2025-11-26.
The cheapest trip from Prague to Frankfurt am Main was searched and found on Nov 24, 2025 with a price of $30
