How much is the train ticket from Greenville to Chicago?

The cheapest train tickets from Greenville to Chicago start from $177. The average price for this train route is around $255. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the train journey from Greenville to Chicago?

The average train ride duration from Greenville to Chicago is 1d 7h, covering a distance of 561 miles (904 km). The quickest train can get you there in 1d 7h and is operated by Amtrak .

Which train operators service the Greenville to Chicago route?

Several major train operators operate on this route with 1 trains available per day.

What is the earliest and latest departure time for the train from Greenville to Chicago?

The earliest train departs from Greenville to Chicago at 2:23am. And the latest train departs at 2:23am.

Train Greenville to Chicago from $169 | Refundable Tickets

Next train departures

Next departures for Greenville to Chicago on January 30
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	2:23am	Greenville Station	1d 9h	10:25am	Chicago (Union Station), IL	Cheapest
Train	2:23am	Greenville Station	1d 7h	8:45am	Chicago (Union Station), IL	Fastest
Train	2:23am	Greenville Station	1d 7h	8:45am	Chicago (Union Station), IL	No tags
Train	2:23am	Greenville Station	1d 9h	10:25am	Chicago (Union Station), IL	No tags

Next departures for Greenville to Chicago on January 31
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Train	2:23am	Greenville Station	1d 7h	8:45am	Chicago (Union Station), IL	CheapestFastest
	Train	2:23am	Greenville Station	1d 7h	8:45am	Chicago (Union Station), IL	No tags

Next departures for Greenville to Chicago on February 1
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	2:23am	Greenville Station	1d 9h	10:25am	Chicago (Union Station), IL	Cheapest
Train	2:23am	Greenville Station	1d 7h	8:45am	Chicago (Union Station), IL	Fastest
Train	2:23am	Greenville Station	1d 7h	8:45am	Chicago (Union Station), IL	No tags
Train	2:23am	Greenville Station	1d 9h	10:25am	Chicago (Union Station), IL	No tags

Last refresh of the prices: Yesterday at 6:04 PM EST.

Compare 2 ways to go from Greenville to Chicago

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Chicago. The journey takes about 21 hours 30 minutes and with fares starting at just $98, it presents an excellent value for a comfortable ride.

11bus per day

21h 30mAverage Duration

565 milesDistance

23kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$98 - $291	Average Duration21h 30m	CO₂ emissions 23kg CO₂e
Train	Average Price$177 - $1,264	Average Duration1d 7h	CO₂ emissions 82kg CO₂e

Train Companies

Amtrak

4/55,751 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5751 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $177

US train companies:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from Greenville, SC to Chicago by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Greenville to Chicago?
The cheapest train tickets from Greenville to Chicago start from $177. The average price for this train route is around $255. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Greenville to Chicago?
The average train ride duration from Greenville to Chicago is 1d 7h, covering a distance of 561 miles (904 km). The quickest train can get you there in 1d 7h and is operated by Amtrak.
Which train operators service the Greenville to Chicago route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Greenville to Chicago?
The earliest train departs from Greenville to Chicago at 2:23am. And the latest train departs at 2:23am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/26

No data

01/27

No data

Today

$256

01/29

No data

01/30

$208

01/31

$224

02/01

$208

02/02

No data

The cheapest trip from Greenville, SC to Chicago was searched and found on Jan 30, 2026 with a price of $208

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Chicago, as early as possible.

You can expect to pay from $208 to $1,466 for a train ticket from Greenville, SC to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $208 which is on 2026-01-30.