Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus terminal of Villazon | Santa Cruz de la Sierra | CheapestFastest |
Last refresh of the prices: Yesterday at 10:12 PM -04.
Get from Villazon to Santa Cruz de la Sierra
The journey takes about 22 hours and with fares starting at just $27, it presents an excellent value for a comfortable ride.
Where are the popular stops in Villazon and Santa Cruz de la Sierra?
Stops in Villazon
- ACalle Suipacha, Villazón, Bolivia
- B
Terminal de Autobuses de Villazon
RN 14, Villazón, Bolivia
Stops in Santa Cruz de la Sierra
- AAv Intermodal, Santa Cruz de la Sierra, Bolivia
Compare bus companies
Based on 6 reviews, the company was rated 2 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. Trans del Sur 1 ticket prices on this trip start at $27
Frequently asked questions about traveling from Villazon, BO to Santa Cruz de la Sierra, BO by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Villazon to Santa Cruz de la Sierra?
The cheapest bus tickets from Villazon to Santa Cruz de la Sierra start from $27. The average price for this route is around $27. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Villazon to Santa Cruz de la Sierra?
The average bus trip duration from Villazon to Santa Cruz de la Sierra is 22h, covering a distance of 335 miles (540 km). The quickest bus can get you there in 22h and is operated by Trans del Sur 1.
Which bus companies service the Villazon to Santa Cruz de la Sierra route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Villazon to Santa Cruz de la Sierra?
The earliest bus departs from Villazon to Santa Cruz de la Sierra at 6:00pm. And the latest bus departs at 6:00pm.
What are the CO₂ emissions for the bus trip from Villazon to Santa Cruz de la Sierra?
A bus trip from Villazon to Santa Cruz de la Sierra generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Villazon, BO to Santa Cruz de la Sierra, BO was searched and found on Nov 28, 2025 with a price of $25To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Villazon, BO to Santa Cruz de la Sierra, BO, as early as possible.
You can expect to pay from $25 to $25 for a bus ticket from Villazon, BO to Santa Cruz de la Sierra, BO based on the last 2 days. You can expect to find the cheapest price for the trip at $25 which is on 2025-12-03.
