Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Tuscaloosa Greyhound Bus Station | Houston Uptown/Upper Kirby | Cheapest | ||||
 | Bus | Tuscaloosa Greyhound Bus Station | Houston Bus Station | Fastest | ||||
| Bus | Tuscaloosa Greyhound Bus Station | Houston Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Tuscaloosa Greyhound Bus Station | Downtown Gray & Smith | No tags | ||||
| Bus | Tuscaloosa Greyhound Bus Station | Houston Bus Station | No tags |
Last refresh of the prices: Yesterday at 4:44 PM CST.
Compare 2 ways to go from Tuscaloosa to Houston
Among the sustainable travel choices, the bus stands out as the good way to reach Houston. The journey takes about 22 hours and with fares starting at just $103, it presents an excellent value for a comfortable ride.
Where are the popular stops in Tuscaloosa and Houston?
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B2121 Main St, Houston, TX 77002
- C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Tuscaloosa to Houston, US by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tuscaloosa to Houston, US was searched and found on Nov 28, 2025 with a price of $154To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tuscaloosa to Houston, US, as early as possible.
You can expect to pay from $154 to $178 for a bus ticket from Tuscaloosa to Houston, US based on the last 2 days. You can expect to find the cheapest price for the trip at $154 which is on 2025-11-28.
Top traveled bus routes
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Popular bus departures from Tuscaloosa
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