Next departures for St. Louis to South Bend on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Gateway Station
South Bend
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Gateway Station
South Bend
Fastest
Next departures for St. Louis to South Bend on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Gateway Station
South Bend
Cheapest
FlixBus + Greyhound Lines, Inc.
Bus
Gateway Station
South Bend
Fastest
Last refresh of the prices: Today at 11:14 AM CST.
Compare 2 ways to go from St. Louis to South Bend
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach South Bend. The journey takes about 11 hours and with fares starting at just $51, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from St. Louis to South Bend by bus
What is the distance between St. Louis and South Bend?
St. Louis and South Bend are 297 miles (479 km) apart.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
No data
11/17
No data
Today
No data
11/19
$47
11/20
No data
11/21
$85
11/22
No data
11/23
No data
The cheapest trip from St. Louis to South Bend was searched and found on Nov 19, 2025 with a price of $47
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to South Bend, as early as possible.
You can expect to pay from $47 to $85 for a bus ticket from St. Louis to South Bend based on the last 2 days. You can expect to find the cheapest price for the trip at $47 which is on 2025-11-19.
What's the cheapest way to go from St. Louis to South Bend?
The bus is the cheapest travel choice for this destination