Next departures for St. Louis to Jackson on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Gateway Station
Jackson (Union Station)
No tags
Bus
Gateway Station
Jackson (Union Station)
No tags
Bus
Gateway Station
Jackson (Union Station)
No tags
FlixBus + Greyhound
Bus
Gateway Station
Jackson (Union Station)
No tags
Greyhound + FlixBus
Bus
Gateway Station
Jackson (Union Station)
No tags
Compare 2 ways to go from St. Louis to Jackson
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Jackson. The journey takes about 15 hours 20 minutes and with fares starting at just $55, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Based on 5594 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $128
Frequently asked questions about traveling from St. Louis to Jackson, MS, US by bus
How far is St. Louis from Jackson?
The distance separating St. Louis and Jackson is 437 miles (705 km).
What are the departure and arrival stations when taking the bus from St. Louis to Jackson?
Most of the buses traveling from St. Louis to Jackson leave from Gateway Station and arrive at Jackson Bus Station. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Jackson?
Once in Jackson, you can start exploring the city and discover its surroundings. The top sights and things to do are Teton Balloon Flights, Jackson Hole Children's Museum, Jackson Hole Adventure Center, Grizzly Country Wildlife Adventures and Jackson Hole Whitewater.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$77
11/18
$77
Today
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11/20
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11/21
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11/22
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11/23
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11/24
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The cheapest trip from St. Louis to Jackson, MS, US was searched and found on Nov 17, 2025 with a price of $77
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Jackson, MS, US, as early as possible.
What's the cheapest way to go from St. Louis to Jackson, MS, US?
The bus is the cheapest travel choice for this destination
The cheapest trip from St. Louis to Jackson, MS, US was searched and found on Nov 17, 2025 with a price of $77
The bus is the cheapest travel choice for this destination
