Bus from San Ysidro, CA to San Francisco, US: Tickets & Schedules

Next bus departures

Next departures for San Ysidro to San Francisco on December 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
San Ysidro Bus terminal
San Francisco Bus StationCheapestFastest

Last refresh of the prices: Yesterday at 5:34 AM PST.

Get from San Ysidro to San Francisco

This route is served by bus only

The journey takes about 12 hours 15 minutes and with fares starting at just $64, it presents an excellent value for a comfortable ride.

1bus per day
12h 15mAverage Duration
471 milesDistance
19kgCO₂ emissions

Frequently asked questions about traveling from San Ysidro, CA to San Francisco, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from San Ysidro to San Francisco?

    The cheapest bus tickets from San Ysidro to San Francisco start from $64. The average price for this route is around $162. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from San Ysidro to San Francisco?

    The average bus trip duration from San Ysidro to San Francisco is 12h 15m, covering a distance of 471 miles (759 km). The quickest bus can get you there in 11h 15m and is operated by Greyhound.

  3. Which bus companies service the San Ysidro to San Francisco route?

    Several major bus companies operate on this route with 1 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from San Ysidro to San Francisco?

    The earliest bus departs from San Ysidro to San Francisco at 6:00am. And the latest bus departs at 7:00pm.

  5. What are the CO₂ emissions for the bus trip from San Ysidro to San Francisco?

    A bus trip from San Ysidro to San Francisco generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from San Ysidro to San Francisco?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.

  7. Which bus company has the best Wi-Fi from San Ysidro to San Francisco?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from San Ysidro to San Francisco?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from San Ysidro to San Francisco?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/29
No data
11/30
No data
Today
No data
12/02
$211
12/03
$198
12/04
$187
12/05
$111
12/06
$64
busbud logoThe cheapest trip from San Ysidro, CA to San Francisco, US was searched and found on Dec 6, 2025 with a price of $64

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to San Francisco, US, as early as possible.

You can expect to pay from $64 to $211 for a bus ticket from San Ysidro, CA to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at $64 which is on 2025-12-06.

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