Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | UCSD Health La Jolla Station | Mesa Bus Stop | No tags | ||||
FlixBus + Greyhound | Bus | San Diego (Old Town-FlixBus) | Mesa Bus Stop | No tags | ||||
FlixBus + Greyhound | Bus | UCSD Health La Jolla Station | Mesa Bus Stop | No tags | ||||
 | Bus | Greyhound Bus Stop | Mesa Bus Stop | No tags | ||||
| Bus | Greyhound Bus Stop | Mesa Bus Stop | No tags |
Get from San Diego to Mesa
This route is served by bus only
The journey takes about 12 hours 35 minutes and with fares starting at just $57, it presents an excellent value for a comfortable ride.
8bus per day
12h 35mAverage Duration
312 milesDistance
13kgCO₂ emissions
Where are the popular stops in San Diego and Mesa?
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Stops in Mesa
- A
Mesa Bus Station
1423 S Country Club , Mesa, AZ 85210, USA
Compare bus companies
US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about traveling from San Diego, CA, US to Mesa by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/21
No data
11/22
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Today
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11/24
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11/25
No data
11/26
$76
11/27
No data
11/28
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The cheapest trip from San Diego, CA, US to Mesa was searched and found on Nov 26, 2025 with a price of $76To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Mesa, as early as possible.
You can expect to pay from $76 to $76 for a bus ticket from San Diego, CA, US to Mesa based on the last 2 days. You can expect to find the cheapest price for the trip at $76 which is on 2025-11-26.
