Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | San Antonio Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | San Antonio Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Pearl District | Winston Salem Greyhound Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | San Antonio Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | San Antonio Bus Station | Winston Salem Greyhound Bus Station | No tags |
Get from San Antonio to Winston-Salem
The journey takes about 1 day, 8 hours 45 minutes and with fares starting at just $138, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Antonio and Winston-Salem?
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C4407 S PanAm Expy #101, San Antonio, TX 78225, USA
- D165 Bowie St, San Antonio, 78205
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
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Frequently asked questions about traveling from San Antonio, US to Winston-Salem by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Antonio to Winston-Salem?
The cheapest bus tickets from San Antonio to Winston-Salem start from $138. The average price for this route is around $182. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Antonio to Winston-Salem?
The average bus trip duration from San Antonio to Winston-Salem is 1d 8h, covering a distance of 1151 miles (1857 km). The quickest bus can get you there in 1d 3h and is operated by FlixBus.
Which bus companies service the San Antonio to Winston-Salem route?
Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, FlixBus, Valley Transit.
What is the earliest and latest departure time for the bus from San Antonio to Winston-Salem?
The earliest bus departs from San Antonio to Winston-Salem at 1:05am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from San Antonio to Winston-Salem?
A bus trip from San Antonio to Winston-Salem generates an estimated 46 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from San Antonio to Winston-Salem?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from San Antonio to Winston-Salem?
Based on reviews on Busbud, the bus company Valley Transit has the best Wi-Fi rating with a score of 2.8.
Which bus company has the most timely service from San Antonio to Winston-Salem?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Antonio to Winston-Salem?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Antonio, US to Winston-Salem was searched and found on Jan 28, 2026 with a price of $131To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Winston-Salem, as early as possible.
You can expect to pay from $131 to $158 for a bus ticket from San Antonio, US to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $131 which is on 2026-01-28.
