Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Aeroporto Ciampino Airport (CIA) | Brussels South (Gare du Midi) | No tags | ||||
| Bus | Aeroporto Ciampino Airport (CIA) | Brussels-North (Gare du Nord) | No tags | ||||
| Bus | Aeroporto Ciampino Airport (CIA) | Midi | No tags | ||||
| Bus | Rome Anagnina | Brussels Airport | No tags | ||||
| Bus | Rome Anagnina | Midi | No tags |
Compare 2 ways to go from Rome to Brussels
Among the sustainable travel choices, the carpool stands out as the good way to reach Brussels. The journey takes about 15 hours and with fares starting at just $145, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$74 - $381 | Average Duration1d 6h | 29kg CO₂e | ||
Carpool | Average Price$145 - $145 | Average Duration15h | 49kg CO₂e |
Where are the popular stops in Rome and Brussels?
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
Compare bus companies
Frequently asked questions about traveling from Rome to Brussels by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Rome to Brussels?
The cheapest bus tickets from Rome to Brussels start from $74. The average price for this route is around $155. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rome to Brussels?
The average bus trip duration from Rome to Brussels is 1d 6h, covering a distance of 728 miles (1174 km). The quickest bus can get you there in 22h 30m and is operated by FlixBus.
Which bus companies service the Rome to Brussels route?
Several major bus companies operate on this route with 18 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.
What is the earliest and latest departure time for the bus from Rome to Brussels?
The earliest bus departs from Rome to Brussels at 12:10am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Rome to Brussels?
A bus trip from Rome to Brussels generates an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Rome to Brussels?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1058 reviews.
Which bus company has the best Wi-Fi from Rome to Brussels?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Rome to Brussels?
According to Busbud traveller reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Rome to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Brussels was searched and found on Dec 20, 2025 with a price of $118To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Brussels, as early as possible.
You can expect to pay from $118 to $304 for a bus ticket from Rome to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $130 which is on 2025-12-22.
