Next departures for Prague to Luxembourg on November 21
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Vehicle type
Departure time
Departure location
Trip duration
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Recommended
Price and booking link
Bus
Florenc
P+R Bouillon
CheapestFastest
Last refresh of the prices: Last Monday at 9:30 PM CET.
Compare 2 ways to go from Prague to Luxembourg
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Luxembourg. The journey takes about 15 hours 10 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 1057 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the departure location and the value for money but often complained with the wifi. RegioJet ticket prices on this trip start at $44
Based on 11139 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $81
Frequently asked questions about traveling from Prague to Luxembourg by bus
How far is Prague from Luxembourg?
Prague and Luxembourg are 370 miles (597 km) apart.
What are the departure and arrival stations when taking the bus from Prague to Luxembourg?
Most of the buses traveling from Prague to Luxembourg leave from PRG Airport and arrive at Luxembourg. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
No data
11/18
$60
Today
No data
11/20
No data
11/21
$48
11/22
No data
11/23
No data
11/24
No data
The cheapest trip from Prague to Luxembourg was searched and found on Nov 21, 2025 with a price of $48
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Luxembourg, as early as possible.
You can expect to pay from $48 to $60 for a bus ticket from Prague to Luxembourg based on the last 2 days. You can expect to find the cheapest price for the trip at $48 which is on 2025-11-21.
What's the cheapest way to go from Prague to Luxembourg?
The bus is the cheapest travel choice for this destination
The cheapest trip from Prague to Luxembourg was searched and found on Nov 21, 2025 with a price of $48
The bus is the cheapest travel choice for this destination