Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Estación Paysandú | Estación Terminal de Ómnibius, Santa Fe | CheapestFastest | ||||
| Bus | Estación Paysandú | Estación Terminal de Ómnibius, Santa Fe | No tags |
Last refresh of the prices: Last Monday at 11:31 PM -03.
Get from Paysandú to Santa Fe
This route is served by bus only
The journey takes about 5 hours and with fares starting at just $76, it presents an excellent value for a comfortable ride.
1bus per day
5hAverage Duration
161 milesDistance
6kgCO₂ emissions
Where are the popular stops in Paysandú and Santa Fe?
Stops in Paysandú
- ACerrito 1305, 60000 Paysandú, Departamento de Paysandú, Uruguay
Stops in Santa Fe
- A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
Compare bus companies
Frequently asked questions about traveling from Paysandú to Santa Fe, AR by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
No data
11/25
No data
Today
$72
11/27
No data
11/28
$90
11/29
No data
11/30
No data
12/01
No data
The cheapest trip from Paysandú to Santa Fe, AR was searched and found on Nov 26, 2025 with a price of $72To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Paysandú to Santa Fe, AR, as early as possible.
You can expect to pay from $72 to $117 for a bus ticket from Paysandú to Santa Fe, AR based on the last 2 days. You can expect to find the cheapest price for the trip at $90 which is on 2025-11-28.
