Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Panama City Beach Station | Memphis Bus Station | Cheapest | ||||
| Bus | Panama City Beach Station | Memphis Bus Station | Fastest | ||||
| Bus | Panama City Beach Station | Memphis Bus Station | No tags |
Last refresh of the prices: Today at 3:54 AM CST.
Get from Panama City to Memphis
The journey takes about 18 hours 35 minutes and with fares starting at just $139, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and Memphis?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Panama City, US to Memphis, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panama City to Memphis?
The cheapest bus tickets from Panama City to Memphis start from $139. The average price for this route is around $144. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to Memphis?
The average bus trip duration from Panama City to Memphis is 18h 35m, covering a distance of 416 miles (671 km). The quickest bus can get you there in 15h 55m and is operated by Greyhound.
Which bus companies service the Panama City to Memphis route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Panama City to Memphis?
The earliest bus departs from Panama City to Memphis at 7:30am. And the latest bus departs at 9:40pm.
What are the CO₂ emissions for the bus trip from Panama City to Memphis?
A bus trip from Panama City to Memphis generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to Memphis, TN was searched and found on Jan 8, 2026 with a price of $128To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Memphis, TN, as early as possible.
You can expect to pay from $128 to $238 for a bus ticket from Panama City, US to Memphis, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $128 which is on 2026-01-08.
Top traveled bus routes
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Popular bus departures from Panama City
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