Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Hbf | Prague (Central Bus Station Florenc) | CheapestFastest | |||||
| Hbf | PRG Airport | No tags | |||||
Flixtrain + Flixbus | Hbf | Prague (Main Station - parking) | No tags | |||||
| Hbf | Prague (Central Bus Station Florenc) | No tags | |||||
Flixtrain + Flixbus | Hbf | Prague (Central Bus Station Florenc) | No tags |
Last refresh of the prices: Today at 6:23 AM CET.
Compare 3 ways to go from Osnabrück to Prague
Among the sustainable travel choices, the bus stands out as the good way to reach Prague. The journey takes about 12 hours 35 minutes and with fares starting at just $49, it presents an excellent value for a comfortable ride.
Where are the popular stops in Osnabrück and Prague?
Stops in Osnabrück
- AHamburger Str. 5, 49084 Osnabrück, Germany
- B
Salzmarkt
Johannisstraße, 49074 Osnabrück, , Germany
Stops in Prague
- AChlumecká, 198 00 Praha 20, Czech Republic
- BAviatická, 161 08, Praha 6, Czechia
- CTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- DKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F300/8 Wilsonova, 110 00 Praha, Czechia
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Osnabrück to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Osnabrück to Prague?
The cheapest bus tickets from Osnabrück to Prague start from $49. The average price for this route is around $89. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Osnabrück to Prague?
The average bus trip duration from Osnabrück to Prague is 12h 35m, covering a distance of 318 miles (512 km). The quickest bus can get you there in 10h 15m and is operated by FlixBus.
Which bus companies service the Osnabrück to Prague route?
Several major train operators operate on this route with 7 trains available per day.
What is the earliest and latest departure time for the bus from Osnabrück to Prague?
The earliest bus departs from Osnabrück to Prague at 2:00am. And the latest bus departs at 8:25pm.
What are the CO₂ emissions for the bus trip from Osnabrück to Prague?
A bus trip from Osnabrück to Prague generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Osnabrück to Prague was searched and found on Dec 28, 2025 with a price of $63To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Osnabrück to Prague, as early as possible.
You can expect to pay from $63 to $88 for a bus ticket from Osnabrück to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $63 which is on 2025-12-28.
