Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Bus Station | CheapestFastest | ||||
 | Bus | Orlando Bus Station | Bus Station | No tags |
Last refresh of the prices: Today at 12:41 AM EST.
Get from Orlando to Myrtle Beach
The journey takes about 11 hours 50 minutes and with fares starting at just $69, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Myrtle Beach?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Orlando Myrtle Beach recent customer reviews
Poor seating, bus from Orlando had weird odour
Shaniqueica G.
Frequently asked questions about traveling from Orlando to Myrtle Beach by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Orlando to Myrtle Beach?
The cheapest bus tickets from Orlando to Myrtle Beach start from $69. The average price for this route is around $101. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Myrtle Beach?
The average bus trip duration from Orlando to Myrtle Beach is 11h 50m, covering a distance of 385 miles (621 km). The quickest bus can get you there in 19h 10m and is operated by Greyhound.
Which bus companies service the Orlando to Myrtle Beach route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Orlando to Myrtle Beach?
The earliest bus departs from Orlando to Myrtle Beach at 4:00am. And the latest bus departs at 8:40pm.
What are the CO₂ emissions for the bus trip from Orlando to Myrtle Beach?
A bus trip from Orlando to Myrtle Beach generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Myrtle Beach was searched and found on Jan 14, 2026 with a price of $71To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Myrtle Beach, as early as possible.
You can expect to pay from $71 to $168 for a bus ticket from Orlando to Myrtle Beach based on the last 2 days. You can expect to find the cheapest price for the trip at $71 which is on 2026-01-14.
