Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Lines, Inc. Philadelphia Myrtle Beach recent customer reviews
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Philadelphia, PA to Myrtle Beach by bus
What is the travel distance from Philadelphia to Myrtle Beach?
The distance between the two cities is 479 miles (772 km).
What are the departure and arrival stations when taking the bus from Philadelphia to Myrtle Beach?
The majority of buses traveling from Philadelphia to Myrtle Beach start their journey at Philadelphia Airport and wind up at Bus Station. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Myrtle Beach?
Once in Myrtle Beach, you can start exploring the city and discover its surroundings. The top sights and things to do are Family Kingdom Amusement Park, Wild Water and Wheels, Wonderworks, Myrtle Waves Water Park and Broadway Grand Prix.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$65
11/20
$124
Today
$135
11/22
$135
11/23
$102
11/24
$109
11/25
$121
11/26
$176
The cheapest trip from Philadelphia, PA to Myrtle Beach was searched and found on Nov 19, 2025 with a price of $65
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Myrtle Beach, as early as possible.
You can expect to pay from $65 to $317 for a bus ticket from Philadelphia, PA to Myrtle Beach based on the last 2 days. You can expect to find the cheapest price for the trip at $102 which is on 2025-11-23.