Next departures for New Orleans to San Diego on December 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Intl Airport, 900 Airline Dr
Downtown SD (Seaport)
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
UCSD Health La Jolla Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
UCSD Health La Jolla Station
No tags
Bus
New Orleans Bus Station
Greyhound Bus Stop
No tags
Bus
New Orleans Bus Station
Greyhound Bus Stop
No tags
Next departures for New Orleans to San Diego on December 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
UCSD Health La Jolla Station
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
UCSD Health La Jolla Station
Fastest
Bus
New Orleans Bus Station
Greyhound Bus Stop
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
Downtown SD (Seaport)
No tags
Bus
New Orleans Bus Station
Greyhound Bus Stop
No tags
Next departures for New Orleans to San Diego on December 30
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
San Diego (Old Town-FlixBus)
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
UCSD Health La Jolla Station
Fastest
Bus
New Orleans Bus Station
Greyhound Bus Stop
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
Downtown SD (Seaport)
No tags
Bus
New Orleans Bus Station
Greyhound Bus Stop
No tags
Next departures for New Orleans to San Diego on December 31
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
UCSD Health La Jolla Station
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
New Orleans Bus Station
Greyhound Bus Stop
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
UCSD Health La Jolla Station
No tags
Bus
New Orleans Bus Station
Greyhound Bus Stop
No tags
Next departures for New Orleans to San Diego on January 1
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Intl Airport, 900 Airline Dr
UCSD Health La Jolla Station
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
UCSD Health La Jolla Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
New Orleans Bus Station
Greyhound Bus Stop
No tags
Greyhound Lines, Inc. + FlixBus
Bus
New Orleans Bus Station
UCSD Health La Jolla Station
No tags
Last refresh of the prices: Today at 3:41 AM CST.
Compare 2 ways to go from New Orleans to San Diego
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach San Diego. The journey takes about 2 days, 4 hours 45 minutes and with fares starting at just $147, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from New Orleans to San Diego, CA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from New Orleans to San Diego?
The cheapest bus tickets from New Orleans to San Diego start from $147. The average price for this route is around $337. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from New Orleans to San Diego?
The average bus trip duration from New Orleans to San Diego is 2d 4h, covering a distance of 1606 miles (2590 km). The quickest bus can get you there in 2d 1h and is operated by Greyhound.
Which bus companies service the New Orleans to San Diego route?
Several major bus companies operate on this route with 11 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from New Orleans to San Diego?
The earliest bus departs from New Orleans to San Diego at 6:55am. And the latest bus departs at 6:10pm.
What are the CO₂ emissions for the bus trip from New Orleans to San Diego?
A bus trip from New Orleans to San Diego generates an estimated 65 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from New Orleans to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from New Orleans to San Diego?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from New Orleans to San Diego?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from New Orleans to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12/24
$184
12/25
$255
Today
$405
12/27
$344
12/28
$274
12/29
$389
12/30
$373
12/31
$359
The cheapest trip from New Orleans to San Diego, CA, US was searched and found on Dec 24, 2025 with a price of $184
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to San Diego, CA, US, as early as possible.
You can expect to pay from $184 to $444 for a bus ticket from New Orleans to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $274 which is on 2025-12-28.
What's the cheapest way to go from New Orleans to San Diego, CA, US?
The bus is the cheapest travel choice for this destination