Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus Station | Tuscaloosa Greyhound Bus Station | CheapestFastest |
Last refresh of the prices: Last Saturday at 5:30 PM EST.
Get from Myrtle Beach to Tuscaloosa
The journey takes about 14 hours 40 minutes and with fares starting at just $82, it presents an excellent value for a comfortable ride.
Where are the popular stops in Myrtle Beach and Tuscaloosa?
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Myrtle Beach to Tuscaloosa by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Myrtle Beach to Tuscaloosa?
The cheapest bus tickets from Myrtle Beach to Tuscaloosa start from $82. The average price for this route is around $82. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Myrtle Beach to Tuscaloosa?
The average bus trip duration from Myrtle Beach to Tuscaloosa is 14h 40m, covering a distance of 500 miles (806 km). The quickest bus can get you there in 14h 40m and is operated by Greyhound.
Which bus companies service the Myrtle Beach to Tuscaloosa route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Myrtle Beach to Tuscaloosa?
The earliest bus departs from Myrtle Beach to Tuscaloosa at 1:55pm. And the latest bus departs at 1:55pm.
What are the CO₂ emissions for the bus trip from Myrtle Beach to Tuscaloosa?
A bus trip from Myrtle Beach to Tuscaloosa generates an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Myrtle Beach to Tuscaloosa was searched and found on Jan 6, 2026 with a price of $74To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to Tuscaloosa, as early as possible.
You can expect to pay from $74 to $74 for a bus ticket from Myrtle Beach to Tuscaloosa based on the last 2 days. You can expect to find the cheapest price for the trip at $74 which is on 2026-01-09.
Top traveled bus routes
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Popular bus departures from Myrtle Beach
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