Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Greyhound Station | Gainesville Bus Stop | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Station | Rosa Parks Station | Fastest | ||||
| Bus | Greyhound Station | Gainesville Bus Stop | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Station | Rosa Parks Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Station | Rosa Parks Station | No tags |
Last refresh of the prices: Last Friday at 10:30 AM CST.
Get from Mobile to Gainesville
The journey takes about 14 hours 5 minutes and with fares starting at just $135, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mobile and Gainesville?
Stops in Gainesville
- A700 SE 3rd St, Gainesville, FL 32601
- B3509 SW Williston Rd, Gainesville, FL 32608, USA
- C101 NE 23rd Ave, Gainesville, FL 32609
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Mobile to Gainesville, FL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mobile to Gainesville?
The cheapest bus tickets from Mobile to Gainesville start from $135. The average price for this route is around $148. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mobile to Gainesville?
The average bus trip duration from Mobile to Gainesville is 14h 5m, covering a distance of 352 miles (568 km). The quickest bus can get you there in 13h 30m and is operated by Greyhound.
Which bus companies service the Mobile to Gainesville route?
Several major train operators operate on this route with 6 trains available per day.
What is the earliest and latest departure time for the bus from Mobile to Gainesville?
The earliest bus departs from Mobile to Gainesville at 3:45am. And the latest bus departs at 3:55pm.
What are the CO₂ emissions for the bus trip from Mobile to Gainesville?
A bus trip from Mobile to Gainesville generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mobile to Gainesville, FL was searched and found on Dec 30, 2025 with a price of $137To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to Gainesville, FL, as early as possible.
You can expect to pay from $137 to $138 for a bus ticket from Mobile to Gainesville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $137 which is on 2025-12-30.
