What is the travel distance from Middletown to Syracuse?

Middletown and Syracuse are 141 miles (227 km) apart.

What are the departure and arrival stations when taking the bus from Middletown to Syracuse?

The majority of buses traveling from Middletown to Syracuse start their journey at Exit 122 Park & Ride and wind up at Regional Transportation Center. These are the most popular departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What are the best sights and things to do in Syracuse?

Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are Erie Canal Museum, The Fun Warehouse, Landmark Theatre, Regal Destiny USA Stadium 19 IMAX & RPX and Webster Pond.

Bus Middletown to Syracuse from $60 | Refundable Tickets

Previously seen trips

Next departures for Middletown to Syracuse on November 24
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:30am	Exit 122 Park & Ride	7h 45m	3:15pm	Amtrak Station	No tags
Bus	7:30am	Exit 122 Park & Ride	8h 15m	3:45pm	SYR Airport	No tags
Bus	11:00am	Exit 122 Park & Ride	4h 45m	3:45pm	SYR Airport	No tags
Bus	11:00am	Exit 122 Park & Ride	4h 15m	3:15pm	Amtrak Station	No tags
Bus	5:00pm	Exit 122 Park & Ride	7h 45m	12:45am	Amtrak Station	No tags

Get from Middletown to Syracuse

This route is served by bus only

The journey takes about 3 hours 40 minutes and with fares starting at just $68, it presents an excellent value for a comfortable ride.

2bus per day

3h 40mAverage Duration

146 milesDistance

6kgCO₂ emissions

Where are the popular stops in Middletown and Syracuse?

Stops in Middletown

A
Exit 122 Park & Ride
Exit 122 Park and Ride, Wallkill, NY 10941, USA
Visit page

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
C
Syracuse Airport
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Compare bus companies

Adirondack Trailways

4/51,126 reviews

Staff4.6

Timeliness4.3

Cleanliness4.8

Wifi2.4

OurBus

4/53,151 reviews

Staff4.4

Timeliness4.1

Cleanliness4.3

Wifi3.1

With about 1 daily trips between Middletown and Syracuse, Ourbus offers competitive fares, clean and comfortable intercity bus travel. Their buses have free WiFi, clean bathrooms, complimentary bottled water, extra legroom and power outlets. They are known for providing excellent customer service, reflecting one of the industry's highest review rates. OurBus does not charge fees to reschedule tickets, which can be changed up to 30 minutes before travel time.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Middletown, NY, US to Syracuse, US by bus

What is the travel distance from Middletown to Syracuse?
What are the departure and arrival stations when taking the bus from Middletown to Syracuse?
What are the best sights and things to do in Syracuse?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/22

No data

11/23

$90

Today

No data

11/25

No data

11/26

No data

11/27

No data

11/28

$69

11/29

No data

The cheapest trip from Middletown, NY, US to Syracuse, US was searched and found on Nov 28, 2025 with a price of $69

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Middletown, NY, US to Syracuse, US, as early as possible.

You can expect to pay from $69 to $93 for a bus ticket from Middletown, NY, US to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at $69 which is on 2025-11-28.