What is the travel distance from Mexico City to Panama City?

The distance separating Mexico City and Panama City is 1121 miles (1808 km).

What are the departure and arrival stations when taking the bus from Mexico City to Panama City?

The majority of buses traveling from Mexico City to Panama City start their journey at Norte and wind up at Panama City Greyhound Bus Station. These are the most popular departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What are the best sights and things to do in Panama City?

Once in Panama City, you can start exploring the city and discover its surroundings. The top sights and things to do are Amador Causeway, Bird Watching, The Panama Canal, Casco Antiguo and Panama Viejo.

Bus Mexico City to Panama City from $192 | Compare & Save up to 27%

Next bus departures

Next departures for Mexico City to Panama City on November 23
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	11:05pm	Mexico City Buenavista (Forum)	2d 8h	7:25am	Panama City Beach Station	CheapestFastest
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	10:40pm	Mexico City Buenavista (San Pedro Santa Clara)	2d 8h	7:25am	Panama City Beach Station	No tags

Next departures for Mexico City to Panama City on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	11:05pm	Mexico City Buenavista (Forum)	2d 8h	7:25am	Panama City Beach Station	Cheapest
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	12:20pm	Mexico City Buenavista (Forum)	1d 19h	7:25am	Panama City Beach Station	Fastest
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	11:55am	Mexico City Buenavista (San Pedro Santa Clara)	1d 19h	7:25am	Panama City Beach Station	No tags
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	10:40pm	Mexico City Buenavista (San Pedro Santa Clara)	2d 8h	7:25am	Panama City Beach Station	No tags

Last refresh of the prices: Last Friday at 11:25 AM CST.

Get from Mexico City to Panama City

This route is served by bus only

The journey takes about 2 days, 7 hours 55 minutes and with fares starting at just $192, it presents an excellent value for a comfortable ride.

3bus per day

2d 7hAverage Duration

1116 milesDistance

45kgCO₂ emissions

Where are the popular stops in Mexico City and Panama City?

Stops in Mexico City

A
Norte
Terminal del Norte, Eje Central 271, Magdalena de las Salinas, 07760 Ciudad de México, D.F., Mexico
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B
TAPO
Terminal de Autobuses de Pasajeros de Oriente, Calz. Ignacio Zaragoza 200, 10 de Mayo, 15290 Ciudad de México, CDMX, Mexico
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C
Sur
Terminal del Sur, Av. Taxqueña No. 1320 (Col. Campestre Churubusco), 04200 Coyoacán - Ciudad de Mexico
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D
Zaragoza
Calz. Ignacio Zaragoza 564d, 4 Árboles, 15730 Ciudad de México, CDMX, Mexico
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E
Mexico City Airport
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F
Aeropuerto MEX T2
Calle Economía, Aeropuerto Int de La Cd de México, 15620 Ciudad de México, CDMX, Mexico
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Stops in Panama City

A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401

Frequently asked questions about traveling from Mexico City to Panama City, US by bus

What is the travel distance from Mexico City to Panama City?
What are the departure and arrival stations when taking the bus from Mexico City to Panama City?
What are the best sights and things to do in Panama City?