- Mexico City to Panama City buses
Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc. | Bus | Mexico City Buenavista (Forum) | Panama City Beach Station | Cheapest | ||||
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc. | Bus | Mexico City Buenavista (Forum) | Panama City Beach Station | Fastest | ||||
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc. | Bus | Mexico City Buenavista (San Pedro Santa Clara) | Panama City Beach Station | No tags | ||||
Flix México + Greyhound Lines Mexico + Greyhound Lines, Inc. | Bus | Mexico City Buenavista (San Pedro Santa Clara) | Panama City Beach Station | No tags |
Last refresh of the prices: Last Friday at 11:25 AM CST.
Get from Mexico City to Panama City
The journey takes about 2 days, 7 hours 55 minutes, and with fares starting at just R 3 404, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mexico City and Panama City?
Stops in Mexico City
- ATerminal del Norte, Eje Central 271, Magdalena de las Salinas, 07760 Ciudad de México, D.F., Mexico
- BTerminal de Autobuses de Pasajeros de Oriente, Calz. Ignacio Zaragoza 200, 10 de Mayo, 15290 Ciudad de México, CDMX, Mexico
- CTerminal del Sur, Av. Taxqueña No. 1320 (Col. Campestre Churubusco), 04200 Coyoacán - Ciudad de Mexico
- DCalz. Ignacio Zaragoza 564d, 4 Árboles, 15730 Ciudad de México, CDMX, Mexico
- FCalle Economía, Aeropuerto Int de La Cd de México, 15620 Ciudad de México, CDMX, Mexico
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Frequently asked questions about travelling from Mexico City to Panama City, US by bus
How much does a bus ticket from Mexico City to Panama City cost?
The bus ticket price from Mexico City to Panama City starts at R 3 404. The best way to find cheap bus tickets from Mexico City to Panama City is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Mexico City to Panama City?
The average travel time between Mexico City and Panama City is around 2d 7h, although the fastest bus will take about 1d 19h. This is the time it takes to travel the 1808 km that separates the two cities.
How many daily bus connections are there between Mexico City and Panama City?
The number of buses from Mexico City to Panama City can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Mexico City to Panama City by comparing and selecting the bus that fits your travel style and budget on Busbud.
What are the departure and arrival stations when taking the bus from Mexico City to Panama City?
Buses travelling between Mexico City and Panama City leave from Norte or TAPO and arrive at Panama City Greyhound Bus Station.





