Next departures for Mexicali to Guadalajara on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Tufesa
Nueva Central
Cheapest
Bus
Tufesa
Zapopan Central de Autobuses (Guadalajara)
Fastest
Bus
Mexicali Bus Station
Zapopan Central de Autobuses (Guadalajara)
No tags
Bus
Mexicali Bus Station
Nueva Central
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Next departures for Mexicali to Guadalajara on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Mexicali Centro Civico - Stop
Nueva Central
Cheapest
Bus
Tufesa
Zapopan Central de Autobuses (Guadalajara)
Fastest
Bus
Mexicali(Ejido Puebla) - Stop
Nueva Central
No tags
Bus
Tufesa
Nueva Central
No tags
Bus
Tufesa
Nueva Central
No tags
Next departures for Mexicali to Guadalajara on November 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Mexicali Centro Civico - Stop
Nueva Central
Cheapest
Bus
Tufesa
Zapopan Central de Autobuses (Guadalajara)
Fastest
Bus
Mexicali(Ejido Puebla) - Stop
Nueva Central
No tags
Bus
Tufesa
Nueva Central
No tags
Bus
Mexicali
Av de las Torres
No tags
Next departures for Mexicali to Guadalajara on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Mexicali Centro Civico - Stop
Nueva Central
Cheapest
Bus
Tufesa
Zapopan Central de Autobuses (Guadalajara)
Fastest
Bus
Mexicali(Ejido Puebla) - Stop
Nueva Central
No tags
Bus
Tufesa
Nueva Central
No tags
Bus
Tufesa
Nueva Central
No tags
Next departures for Mexicali to Guadalajara on November 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Mexicali Centro Civico - Stop
Nueva Central
Cheapest
Bus
Tufesa
Zapopan Central de Autobuses (Guadalajara)
Fastest
Bus
Mexicali(Ejido Puebla) - Stop
Nueva Central
No tags
Bus
Tufesa
Nueva Central
No tags
Bus
Tufesa
Nueva Central
No tags
Last refresh of the prices: Today at 10:29 AM PST.
Compare 2 ways to go from Mexicali to Guadalajara
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Guadalajara. The journey takes about 22 hours 10 minutes and with fares starting at just $87, it presents an excellent value for a comfortable ride.
Based on 167 reviews, the company was rated 2.5 stars on Busbud. Travelers were especially satisfied with the seats and the temperature but often complained with the wifi. Elite ticket prices on this trip start at $177
Since 1994, Tufesa has been offering comfortable, safe, and affordable bus travel in the United States (California, Nevada, Utah, Arizona and Texas) and Mexico (Baja California Sur, Sonora, Sinaloa and Guadalajara). Tufesa buses are equipped with comfortable reclining seats, power outlets, bathrooms, and WiFi (only in Mexico). Tickets are non-refundable, but you can exchange them up to 1 hour before travel time for a small fee. The company accepts e-tickets, so you don't have to worry about printing your boarding pass. With over 6 daily trips, you'll surely find a convenient trip that fits your needs and your schedule.
If you're looking for an affordable, comfortable way to travel through the pacific region of Mexico and the United States, then ACN is a good option. With more than 300 buses, the company travels through over 700 routes in the two countries, connecting over 50 cities with an average of 600 daily buses. With a modern fleet, ACN buses have WiFi, reclining comfy seats, power outlets, onboard entertainment, and bathrooms.
Based on 23 reviews, the company was rated 1.5 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the power outlets. Autotravel ticket prices on this trip start at $128
Based on 167 reviews, the company was rated 2.5 stars on Busbud. Travelers were especially satisfied with the seats and the temperature but often complained with the wifi. Elite ticket prices on this trip start at $177
Since 1994, Tufesa has been offering comfortable, safe, and affordable bus travel in the United States (California, Nevada, Utah, Arizona and Texas) and Mexico (Baja California Sur, Sonora, Sinaloa and Guadalajara). Tufesa buses are equipped with comfortable reclining seats, power outlets, bathrooms, and WiFi (only in Mexico). Tickets are non-refundable, but you can exchange them up to 1 hour before travel time for a small fee. The company accepts e-tickets, so you don't have to worry about printing your boarding pass. With over 6 daily trips, you'll surely find a convenient trip that fits your needs and your schedule.
TIM Express offers 1 daily buses from Mexicali to Guadalajara. Though the average price for this trip is $123, you can find tickets starting at $123. The trip between the two cities usually takes about 1740.
Based on 3 reviews, the company was rated 3.6 stars on Busbud. Travelers were especially satisfied with the departure location and the timeliness but often complained with the wifi. Interbus de Sinaloa ticket prices on this trip start at $105
Based on 32 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the departure location and the cleanliness but often complained with the wifi. Aguacaliente ticket prices on this trip start at $167
Coordinados del Norte offers 1 daily buses from Mexicali to Guadalajara. Though the average price for this trip is $141, you can find tickets starting at $127. The trip between the two cities usually takes about 2400.
Based on 160 reviews, the company was rated 3.1 stars on Busbud. Travelers were especially satisfied with the ticket access and the seats but often complained with the wifi. Chihuahuenses ticket prices on this trip start at $149
Based on 15 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the seats and the cleanliness but often complained with the timeliness. ELITE SELECT ticket prices on this trip start at $150
Based on 736 reviews, the company was rated 3.4 stars on Busbud. Travelers were especially satisfied with the seats and the departure location but often complained with the wifi. Futura ticket prices on this trip start at $143
Frequently asked questions about traveling from Mexicali to Guadalajara, MX by bus
What is the distance between Mexicali and Guadalajara?
About 1110 miles (1790 km) separate Mexicali and Guadalajara.
What are the departure and arrival stations when taking the bus from Mexicali to Guadalajara?
If you're headed to Guadalajara from Mexicali, chances are that your bus will leave from Terminal de Autobuses de Mexicali and arrive at Nueva Central. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/21
$93
11/22
$161
Today
$92
11/24
$93
11/25
$92
11/26
$93
11/27
$93
11/28
$92
The cheapest trip from Mexicali to Guadalajara, MX was searched and found on Nov 25, 2025 with a price of $92
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Guadalajara, MX, as early as possible.
You can expect to pay from $92 to $162 for a bus ticket from Mexicali to Guadalajara, MX based on the last 2 days. You can expect to find the cheapest price for the trip at $92 which is on 2025-11-25.
Usually Tufesa will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Mexicali to Guadalajara, MX was searched and found on Nov 25, 2025 with a price of $92
