Bus Tickets from Lyon to Palermo

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TodayJul 9
TomorrowJul 10
FriJul 11
SatJul 12
SunJul 13
from $139
MonJul 14
TueJul 15
WedJul 16

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 13 at
    Departure city: Lyon
    Departure location: Aéroport LYS
    Arrival time: July 14 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 13 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: July 14 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: July 13 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: July 14 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: July 13 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: July 14 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: July 13 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: July 15 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Accepted payments

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Bus Lyon to Palermo: Trip Overview

Average ticket price$191
Average bus trip duration1d 7h
Number of daily buses4
Earliest bus departure3:25am
Distance685 miles (1104 km)
Latest bus departure11:30pm

Lyon to Palermo Bus

With Busbud, comparing and booking tickets for a bus from Lyon to Palermo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Lyon to Palermo from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Lyon to Palermo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Lyon - Palermo

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/07
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07/08
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Today
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07/10
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07/11
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07/12
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07/13
$135
07/14
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busbud logoThe cheapest trip from Lyon to Palermo was searched and found on Jul 13, 2025 with a price of $135

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Palermo, as early as possible.

You can expect to pay from $135 to $248 for a bus ticket from Lyon to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $135 which is on 2025-07-13.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Lyon to Palermo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Lyon to Palermo, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Lyon to Palermo that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Lyon to Palermo while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Lyon by bus?

Bus from Lyon to Palermo

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